Alternative treatment PD

[Difg]

Hello! My friend started taking dihexa and says she felt a relief in the movements. Does anyone else have experience with Dihexa? I read that it restores nerve cells and turns the disease around. Unfortunately, it is only sold in America.

[Hidden]

Hi Difg thank you for this. I want to try it if I can figure out how to access it.

en.m.wikipedia.org/wiki/Dihexa

Dihexa (developmental code name PNB-0408), also known as N-hexanoic-Tyr-Ile-(6) aminohexanoic amide, is an oligopeptide drug derived from angiotensin IV that binds with high affinity to hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met. The compound has been found to potently improve cognitive function in animal models of Alzheimer's disease-like mental impairment.[1][2][3][4][5][6][7][8][9][10] In an assay of neurotrophic activity, Dihexa was found to be seven orders of magnitude more potent than brain-derived neurotrophic factor.[11]

[Hidden]

Hi Difg - Is she taking it orally? What is the dosage?

[Difg in reply to Hidden]

Yes, orally,7 mg

[Lucal in reply to Difg]

Where can you buy It ?

[Difg in reply to Lucal]

If you live in stati uniti can buy here tailormadecompounding.com/a...

[Jjrr]

it looks like MJF funded an animal study in 2013.

Final Outcome

The goal of this project was to begin to evaluate the therapeutic potential of a small molecule activator of a growth factor, hepatocyte growth factor, which is known to protect nerve cells from damage, stimulate new connections among nerve cells, and induce the production of new neurons form stem cells. The hypothesis guiding the study was that the drug candidate Dihexa would be effective at restoring motor function that was lost in a standard pre-clinical model of Parkinson’s disease. The results of this study confirmed this hypothesis, demonstrating that Dihexa, given by abdominal injection or orally, completely restored lost motor function. Moreover, staining for tyrosine hydroxylase (TH), a marker for the dopamine neurons that were lost following chemical lesioning, returned to near normal after 34 days of treatment. Studies are still ongoing to determine whether this recovery of TH staining was due to the presence of new nerve cells and/or the expansion of the appendages of surviving neurons.

here are academic pubs / patent application

doi.org/10.1016/j.pneurobio...

nnjournal.net/article/view/...

patents.google.com/patent/U...

[SilentEchoes]

Thanks for sharing - very interesting. Not an endorsement, but Dihexa can be purchased here and they ship world wide us.supersmart.com/search.pl...

SE