Marked improvement in PD status after phl... - Cure Parkinson's

Copper-carrying protein, ceruloplasmin, is also tasked with removal of toxic iron ions from the brain. When ceruloplasmin is low, it cannot accomplish this task, with resultant iron accumulation in motor control centers. Most PD patients have a low ceruloplasmin level.

Low ceruloplasmin is also the hallmark of Wilson’s disease, a genetic condition characterized by progressive copper accumulation in tissues. Interestingly, there is at least one investigator asserting that PD could well be the milder heterozygote form of Wilson’s disease

dovepress.com/ceruloplasmin...

bmcneurol.biomedcentral.com...

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Astra7 in reply to MehmetKutlu4 years ago

I had my copper checked by an integrative gp who said it was very high. She sold me something to remove it, but when I mentioned it to my neurologist he got very agitated and said low copper was the last thing I want!

I’m seeing him next week so I’ll ask him about these issues. He can earn his $200 for a change!

I wonder if he could do a brain biopsy without damaging me?

kaypeeoh4 years ago

I couldn't bring up the report on my laptop. 20 years ago I read a study that showed people who donated blood regularly had a lower incidence of all forms of cardiac disease. One theory is phlebotomy forces the marrow to release new red cells. These young cells are elastic. They can bend and fold to move through smaller arteries. BTW, ozone acts similarly on red cells. I donated blood four times a year for over 20 years. I was diagnosed with PD but don't have the more serious symptoms: No bradykinesia and no 'freezing'. Essentially I have a hand tremor and small handwriting. I had to stop donating after I was put on drugs to treat Multiple Sclerosis. I stopped those drugs last year and hope to continue donating after the drug 'washout' period.

bepo in reply to kaypeeoh4 years ago

Excellent. Are you familiar with the natural way to treat MS with Dr. Terry Wahls? She had MS while going through medical school, and waes confined to a wheelchair. Now she is very active. The Wahl's Protocol is helpful and can cure MS.

kaypeeoh in reply to bepo4 years ago

I read her book. Her idea of eating 40# of greens per day may be a good idea but seems impractical.

bepo in reply to kaypeeoh4 years ago

Juicing? The juicing of greens is part of the cancer treatment at Gersen Clinic.

MehmetKutlu4 years ago

Thanks for your feedback. I am sorry that you were unable to read the case report from the link. A google search "Parkinson's + phlebotomy" could bring up the report.

In brief; a 43 year-old male with PD and hemochromatosis presents to a Neurology clinic in New Jersey. Motor UPDRS score was 78. During a course of 2 years in which he received maximal medical therapy, his score fell to 66. Subsequently, a decision to proceed with phlebotomy was made, to decrease iron load of the patient. Just after 3 weeks, the motor UPDRS score dropped from 66 to 35 with dramatic decrease in pains and reduction in medication doses.

4 months later, probably due to re-accumulation of iron, the score rose to 51. A repeat phlebotomy was undertaken, which brought the UPDRS score down to 16.

To me, 2 points were notable:

1. This was apparently a relatively mild case of hemochromatosis, since the patient was under Hematology follow-up without treatment, ie, just observation. Phlebotomy decision was made by the Neurology team, not by Hematology.

2. Brain MR of the patient revealed no iron deposition (for which, my neurologist says, MR is highly sensitive. His explanation was: microscopic deposition of iron at the cellular level in basal ganglia).

Phlebotomy, worth a try ?