PD: Colonic dysmotility, Enteric α-Synuclein, FMT, Microbiota Dysfunction - a delightful miscellany

[aspergerian]

PD: Colonic dysmotility, Enteric α-Synuclein, FMT, Microbiota Dysfunction - delightful miscellany.

Accumulation of Alpha-synuclein Causes Colonic Dysmotility Independently of Enteric Nervous Damage in the Early Stage of Parkinson's Disease.

2013.

ncbi.nlm.nih.gov/pubmed/236...

ncbi.nlm.nih.gov/pmc/articl...

Alpha-Synuclein Pathology and the Role of the Microbiota in Parkinson’s Disease.

2019.

ncbi.nlm.nih.gov/pubmed/236...

ncbi.nlm.nih.gov/pmc/articl...

Relation of Enteric α-Synuclein to Gastrointestinal Dysfunction in Patients With Parkinson’s Disease and in Neurologically Intact Subjects.

Hyo Jeong Lee, et al.

Journal of Neurogastroenterology and Motility 2018; 24(3): 469-478

ncbi.nlm.nih.gov/pmc/articl...

Gut Microbiota Dysfunction as Reliable Non-invasive Early Diagnostic Biomarkers in the Pathophysiology of Parkinson’s Disease: A Critical Review.

2018.

ncbi.nlm.nih.gov/pubmed/292...

Parkinson's Disease: The Emerging Role of Gut Dysbiosis, Antibiotics, Probiotics, and Fecal Microbiota Transplantation.

2019.

ncbi.nlm.nih.gov/pubmed/313...

[Oceanflow]

Thanks again for this interesting post! I wonder who out there is willing to give us specialized faecal transplants? Will our Medicare plans pay for it?

[Blackfeather]

Great post! It's very frustrating that FMT could be of great benefit to our gut health and PD, but in USA, the FDA has restricted its availability.

[aspergerian in reply to Blackfeather]

Problem with FMT: if might soon have high efficacy and would turn attention away from habituatedly ingrained PD pharmaceuticals with low efficacy but high gross sales.

[akgirlsrock]

YouTube video on a man who tried fecal transplant with Parkinson's . The title (Holy shit)

[John_morris71 in reply to akgirlsrock]

youtube.com/watch?v=MLAD4xp...(Not working as expected?)

[Rosenmu]

I'm seeing more mention of antibiotics in relation to diseases such as Parkinsons.

[TomandDon]

Thank you for a very informative post