Next study from Enterin Inc ENT 01 for co... - Cure Parkinson's
Next study from Enterin Inc ENT 01 for constipation. I was in phase 1 study and the stuff worked fine.
God I wish I could do this study!! My enteric nerve has been so compromised! Motility is awful and heartburn is the worst. 🙄😳😩
Maybe there is a location near you.
What are the eligibility requirements, and when and where is the next trial phase?
Go on Enterin Inc's website. They will have press releases
"worked fine"...
any chance you could be a lot more specific. The study specs were somewhat vague if I remember. This phase 1 was all about safety and tolerability so what did it actually improve in terms of your PD symptoms? Anything objective? Or was it purely subjective.
Seems an extreme drug to reduce constipation which is not inherent with PD.
s
Constipation was a primary problem. I forget exactly the day, but probably around the 6-8th day significant improvement occurred and by 10 days it was 95% relieved.
They started me on 6 pills a day and then every 3 days added a pill. When I got to 9 pills, it made me throw up. They wanted me to stay at 8, but I respectfully declined explaining that I was not about to throw up every day for their experiment and if they didn't agree to lower the dose today, I was out.
After the trial ended, the relief lasted 10 days.
One other HU forum member participated in the trial and posted essentially the same experience. That was last year.
The stuff works (on me.)
PS. And I am going to participate in this trial
What you mean not inherent? Constipation is very common in PD.
MBA: Common is NOT "inherent".
IOW, many people have constipation but who are not PD.
s
So, I don't understand what you're saying. Are you saying that constipation is not a Parkinson's symptom that a significant percent, probably half, of PWP deal with?
At one time or another, probably a lot, but what does it matter?
Maybe it's not inherent for you, but for those of us with PD who suffer serious daily constipation it is a real problem
B1 high dose cures really bad constipation for me. Also the only symptom my neurologist asked me about so understood it was a common problem with pwp
Based on the following survey article, it appears that constipation affects greater than 50% of PWPs :
bmcneurol.biomedcentral.com...
So definitely a problem. In the general public, the range is more like 12 to 19%.
Art
Thanks! I’m curious if you saw any other motor benefits besides constipation?
Thanks! I’m curious if you saw any other motor benefits besides constipation?
No, didn't notice anything else.
Biotech firm Enterin will host a webinar to present top-line results from their Phase 2b (KARMET) study in #Parkinsons on Thursday 27th January at 2:30pm EST
Not what you're looking for?
You may also like...
Encouraging results from the phase-I trial! The NADPARK study: A randomized phase I trial of nicotinamide riboside supplementation in PD
The FMT / PD Study Results I Had Been Waiting For Were Released Today And It Was Very Disappointing
Hi i`m a Norwegian 52 year,And I`ve got the Parkinson for about 10 years and i`m in the "Park Vest "study.
I was selected for a clinical trial in Phase 2, for a Mesenchymal Stem Cell Therapy for Parkinson's Disease. Looks promising, any thoughts?
I found this study intriguing. I signed up for it and was accepted. They are still enrolling if it's anybody's cup of tea.
Related Posts
I wonder how many had their whole body shake all over in the night. I was vibrating from head to toe.
Today we announced that the US FDA has cleared IND applications for 4dpharmaplc’s LiveBiotherapeutics MRx0005 and MRx0029, Phase I
The Correct Curcumin for Used in "The Effect of Curcumin on Idiopathic Parkinson Disease: A Clinical and Skin Biopsy Study"
I am in the advanced stages of parkinson's. I had to stop working, I worked all my life. What do I do with my time, I feel useless and bored
Transitioning from aNOW product for my levodopa to a purer levodopa and I sense a loss of some benefit in the absence of the NOW caps
