Life Extension's "Dopamind" supplement

[TL500]

Hi All,

Has anyone tried this or what do you think of this for pd with/without PD meds please? Thanks.

lifeextensionaustralia.com/...

[MBAnderson]

Be nice if they would've identified the studies.

Personally, I don't believe, "...Dopa-Mind™ produced a 74% improvement on a standard test of mental acuity." 74% improvement is a lot of improvement (from a barely-known herb.) If this were true, the stuff would be in the water fountains on college campuses.

sciencedirect.com/topics/me...

[TL500 in reply to MBAnderson]

Thanks Marc. Sorry I have trouble understanding the article. Is it possible you give me a summary please? Thanks.

[MBAnderson in reply to TL500]

I added the link because talked about Isovitexin, which got covered below.

[TL500 in reply to MBAnderson]

Thanks Marc

[LAJ12345]

hindawi.com/journals/bmri/2...

Current therapies for patients with Alzheimer’s and Parkinson’s are focused on improving symptoms, such as increased acetylcholine in AD, with benefits in memory and cognition, and those reducing Parkinson’s dopamine degradation without delaying its progression [50]. These therapies are palliative and do not operate in the pathological genesis of neurodegeneration, such as the reduction of OS and neuroinflammation, as well as the modulation of signaling pathways for death and survival of cells. Vitexin has been shown to act in these pathways in preclinical experiments with results that qualify it as a promising molecule for further investigations and development of an adjuvant drug for the treatment of those diseases.

[Parkie- in reply to LAJ12345]

Laj,

Thank you. Interesting study and quotation. The entire point "3.2. Parkinson" of your link is quite impressive.

Your link is about Vitexin, versus Isovitexin for TL500's product link.

Vitexin seems to be sold for research only versus Isovitexin that is available from TL500's link...

So, I am wondering about the difference between the two. I found this link but only the abstract is free.

"A review on the pharmacological effects of vitexin and isovitexin"

sciencedirect.com/science/a...

Seems encouraging:

"Vitexin (apigenin-8-C-glucoside) has recently received increased attention due to its wide range of pharmacological effects, including but not limited to anti-oxidant, anti-cancer, anti-inflammatory, anti-hyperalgesic, and neuroprotective effects. Isovitexin (apigenin-6-C-glucoside), an isomer of vitexin, generally purified together with vitexin, also exhibits diverse biological activities.

Latest research has suggested that vitexin and isovitexin could be potential substitute medicines for diversity diseases, and may be adjuvants for stubborn diseases or health products."

[LAJ12345 in reply to Parkie-]

I think they are isomers, having said that isomers don’t necessarily work the same way, it’s true.

[TL500 in reply to LAJ12345]

You mean it may not be as effective for PD as Vitexin?

[LAJ12345 in reply to TL500]

I’m not sure.

[TL500 in reply to LAJ12345]

Thanks

[TL500 in reply to LAJ12345]

Thanks LAJ. It's an interesting info. Hope it will be available to us and works as said.

[bassofspades]

i tried a bottle. honestly, it did absolutely nothing for me.

[TL500 in reply to bassofspades]

Thanks

[Zardoz]

I tried Life Extension's Dopamind and it did nothing for me.

[TL500]

Thanks

[mgregor6]

I've ordered it 7 or 8 times. Noticed nothing.

[TL500 in reply to mgregor6]

Thanks. I was hoping positive results but so far no one has had good results.