Do you take Miralax?

[Joanne_Joyce]

I would like to hear from people who regularly take more than the recommended dose of Mirialax. I am very tempted to take it more often and would love to find out if it is helpful or not to do so.

[Hidden]

"not to do so". Why overdose laxative? Taking high dose thiamine hcl for Parkinson's relief will end constipation.

[Bruceyg65 in reply to Hidden]

I am never constipated except when taking HDT. I’ve tried 2g and 500mg split across 2 doses per day. I’ll try a third time to see if it is a coincidence. I haven’t been able to remain on it long enough to determine if there is any benefit.

[Axeltoot in reply to Hidden]

Roy, I have Parkinsonism which in turn causes constipation I take Miralax seems to help. What is a high dose of thiamine taken for and how does it help?

[Hidden in reply to Axeltoot]

Diagnosed 2012

My regimen:

The positives: no bradykinesia, I cut my food with a knife, no button difficulties, brush my teeth now w/o needing elect brush, more strength. Getting in and out of bed, turning over is easier. No more constipation. Parkinson's progression stopped. Suppressed all motor and non-motor symptoms...

Entering my 7th year post diagnosis and have not fallen, not once, to the surprise of my neuro. Was seeing neuro every 6th month, last visit he set app one year. He said if needed we could do some changes earlier. He said my condition can change in as little time as one week.

New schedule, now I follow this regimen:

3 x day C/L 50-200 ER : 8 am, 2 pm, 8 pm. Because it is ER, I take with or w/o food.

2 x day (8 am 2g, and 2 pm 2g) Vitacost vitamin B1 (as thiamine HCL) 500mg, easy swallow capsules

B1 Thiamine therapy reference / stop progression, suppress motor and non-motor symptoms:

(Thiamine HCL is oral substitute to injecting B1) 2 x day (morning 2g and at lunch 2g)

Doctor Costantini strategy that I find helpful "thiamine hcl stops the progression forever...".

[Stevenmast in reply to Hidden]

As much as I have benefited from the B1 moving my bowels is not one of them in fact it's got worse! I'm not sure if there's a correlation but it's a big issue for me. I'm going for a colonoscopy on Monday hopefully that comes back good and I'll take it from there.

[ParlePark]

Try psyllium. Natural and works great.

[aspergerian13 in reply to ParlePark]

Enter this into google:

psyllium levodopa.

[parkie13 in reply to aspergerian13]

Good to know.

[Goldencbc]

I used to use it quite a lot before I started B1. I would take it once daily for 3-4 days in a row and would be fine for a few weeks and then it would be needed again. I occasionally still need it or a stool softener. My doctor told me it was fine to use every day. However, overall , taking B1 really changed the situation for the better.

[aspergerian13]

Dare we suspect that B1 is improving mitochondrial function in tissues that participate in motility and digestion?

[gl2238]

I use a Magnesium Oxide Supplement. Works wonders for constipation. I take one either mid day or PM with food or after eating. No problem with constipation.

[gaga1958 in reply to gl2238]

hi, is mag oxide more effective than mag citrate? thx

[gl2238 in reply to gaga1958]

Mag citrate is better absorbed so less is needed but it poses an interaction with one of my meds. I found that a 300mg dose, of Mag Oxide, is adequate, taken after dinner, to work great in mitigating constipation. Mag Oxide is also less expensive. Side effects are nil.

[Rhyothemis in reply to gl2238]

Which one of your meds interacted with the magnesium citrate? Do you have the same problem with other forms of citrate?

[gl2238 in reply to gaga1958]

The answer to your question is that I do not use Miralax.

[tjmclaughlin227]

May I please ask how much B1 everyone takes a day? I have just bought the 500 mg Thiamine HCL for my Mum and was wondering how much to give her. Any feedback appreciated. Thank you

[Hidden in reply to tjmclaughlin227]

Hi tjmclaughlin227: Do you think you should ask a bunch of lay people here or a doctor? What if something happens to her and goes wrong? It's one thing to try this out on oneself and another thing to try it on someone else, especially a loved one. The proponent of this treatment, Dr. Constantini is reportedly not going to be able to help you with the information for a while because he is recovering from a stroke.

Please think this through before you take action.

[tjmclaughlin227 in reply to Hidden]

Thank you so much for your concern for my mum 'malayappan'. If I may please ask for your understanding that many people simply ask a question without feeling the need to 'explain in detail' what they have, or have not done, prior to reaching out. Just because we do not say we have had prior authorisation from the Dr, does not mean we have not.

In answer to your question about 'asking a bunch of lay people'- whilst admittedly there many such bad people around, there are also many ' very good' people who just genuinely wish to share their good fortune, or bad fortune, with others. Their experiences/feedback can then be discussed with Mum's DR, who will ultimately make her own professional decision for my Mum.

To further put your mind at rest, 3 months after having my Mum on this B1 dose that my mum's Dr APPROVED this week for her, we shall be having a blood test to ensure all her levels are still in order BEFORE we discuss whether we raise the dosage or not. This is what we do EVERY TIME we introduce a new medication. Thank you.

[Hidden in reply to tjmclaughlin227]

I wish the best for you and your mum.

[Hidden in reply to tjmclaughlin227]

Blood test? I would not be seeking a normal level. The object is high dose. Safety is this vitamin's record. See webmd. I would keep independent thought regarding Neuro opinion that is not backed by study but only scepticism.

Diagnosed 2012

My regimen:

The positives: no bradykinesia, I cut my food with a knife, no button difficulties, brush my teeth now w/o needing elect brush, more strength. Getting in and out of bed, turning over is easier. No more constipation. Parkinson's progression stopped. Suppressed all motor and non-motor symptoms...

Entering my 7th year post diagnosis and have not fallen, not once, to the surprise of my neuro. Was seeing neuro every 6th month, last visit he set app one year. He said if needed we could do some changes earlier. He said my condition can change in as little time as one week.

New schedule, now I follow this regimen:

3 x day C/L 50-200 ER : 8 am, 2 pm, 8 pm. Because it is ER, I take with or w/o food.

2 x day (8 am 2g, and 2 pm 2g) Vitacost vitamin B1 (as thiamine HCL) 500mg, easy swallow capsules

B1 Thiamine therapy reference / stop progression, suppress motor and non-motor symptoms:

(Thiamine HCL is oral substitute to injecting B1) 2 x day (morning 2g and at lunch 2g)

Doctor Costantini strategy that I find helpful "thiamine hcl stops the progression forever...".

Parky people say the first five years is your honeymoon stage with Parkinson's. After that, progression more rapid.I

I have gone from slow motion to normal motor action since joining the growing number of PwP that have started B1 regimen/protocol. –

Doctor Costantini - “Why is this? Because there is no medicine or drug that is able to affect all of the organs, whereas all of the organs function thanks to Thiamine. An important detail”, adds doctor Costantini, “the Thiamine therapy brings no collateral damage with time”.

Join my facebook group:

"parkinson's thiamine hcl"

facebook.com/groups/2322600... …

Parkinson's Relief, Questions and Answers

[Despe in reply to tjmclaughlin227]

Hello! Blood test results might indicate that B1 is normal, but it's not the plasma level that indicates the need for additional B1. Also, your mother's current condition, age, weight, and other medical conditions will determine amount of B1, either oral or injection. In any event, 500mg B1 is not a dose to worry about. Of course, I am not a doctor but a care spouse whose husband started B1 injections last summer. He has seen a lot of improvements (diagnosed last March). Hope it helps.

[Axeltoot in reply to tjmclaughlin227]

tjmclaughlin227, I had a brainstem stroke in 2007 and developed Parkinsonism in 2008. Does Mum have PD if so how does B1 help!!!

[Sadiedog12 in reply to tjmclaughlin227]

You are Absolutely right in my opinion.

[brills]

Hi - we've been using Linzess (costly prescription) every morning along with Miralax (2 capfuls of miralax into 3/4 of an ozarka water bottle) - and it seems to do the job. One neurologist suggested that if it doesn't work (and it usually does), to add in a capful of magnesium citrate - and that will get you going. We used to take 1 1/2 caps of miralax - but didn't seem to help as much...two caps definitely does. This has been our regimen for the past 5 years believe it or not...ugh. Still have LOTS of gut issues with nausea - everyday - it's terrible...but when he takes Rytary, the gut issues tend to stop for an hour or two (takes about 30 minutes to an hour though ...but I think it's the dopamine begins to "move" the body and the organs as well, and things get better...just wish he had more "on" time.

[vincea]

H, yes I do take Miralax - every day - and I take one Magnesium Citrate, both recommendedby my 'Gastro' doctor. I do not fill the cap to the dosage line, but just below that line. I've had CIC (Chronic Idiopathic Constipation) for about twenty years, but it's no longer in my life. BTW, there were no noticeable side effects by doing this.

[pad10]

i eat 6-9 prunes daily for bone strength and take 600mg of magnesium citrate and drink water and i am good. i also eat 3-5 cups of fruits and veggies ea day and i eat whole grains. if i go off my regime i start having problems.

[SELFMeder in reply to pad10]

my alternative medicine MD says Mag Clycinate is better absorbed.

[Coot18]

according to my doctor, the mechanism for most laxatives is to keep moisture in your gut

his suggestion: drink plenty of water and eat plenty of fiber

If a given medication (B1, C/L, etc) causes constipation, it removes moisture from my gut.

I need to drink even more water, eat even more fiber.

A lay person's assumption based on conversation with doctor, input from you all and this lay person's experience.

hope it helps

and let's not forget, some of the symptoms we are tying to deal with using pills and practices may not be Parkinson's disease, they may be Aging disease.

[GBAMIGOD]

Hi Joanne,

I take normal dose of miralax,drink a lot of water,eat a lot of food rich in fiber and exercise.A combination of all these helps with constipation with overdosing on Miralax.

[ktbate]

I was told by my doc to use a product called Super Aloe (Health Food Store). It works but please note that these products should be taken on a daily basis to become regular. My doc said "No" to Miralax.

[Rscott]

I used to take all kinds of meds for constipation until someone recommended 5tbs aloe daily. I am now regular for the first time in my adult life.

[Hidden]

My husband has PD and constipation. He doesn't generally take more than recommended (in fact at times he is 'regular' with 1/2 dose). However, after a round of antibiotics, he got irregular, and I gave him extra for several days, and that got him back on track, and then I cut back. After his neurologist said that she gave her infant son Miralax for 10 years (until he apparently outgrew his problem), I felt more comfortable with my husband remaining on it indefinitely and flexing the dosage as needed.

[KLDA]

I use Kirkland brand LaxaClear, a knock off of Miralax, daily along with two stool softeners. Both my primary health care physician, and the neurologist I see know my regime. I am not able to eliminate without it. I also take high dose of thiamine daily. I agree with RoyProp if high dose of b-1, thiamine works, this is a better solution. I also take a high dose of thiamine.

[SELFMeder]

I take Miralax and Colace each once or twice a day, as needed to enable my bowel system to function. PD puts your digestive system to sleep...