Curcumin protection of the brain

[parkie13]

naturalmedicinejournal.com/...

Interesting article

[Despe]

Hi Mary! My husband has been taking it for a few months (the specific one). Hopefully, we'll see results as the link suggests.

[parkie13 in reply to Despe]

I also just started few days ago. Hopefully it's going to do some good.

[Despe in reply to parkie13]

Absolutely! Anything that can cross the BBB is good. Personally, I add a tsp of powder to my evening meal and since I love pepper, I load the turmeric with pepper for better absorption.

[parkie13 in reply to Despe]

Hi, after reading doctor blaylock's newsletter I followed his recommendation for Nano curcumin from One Planet Nutrition it is supposed to be able to cross the blood-brain barrier. I'll see if I can tell any difference after a couple months. How long have you been on it?

[Despe in reply to parkie13]

Not me, my husband is the PwP. He started taking it late summer 2018. He is taking Integrative Therapeutics "Theracurmin HP" 2 tablets (600mg), the recommended dose. It is bioavailable curcumin. I will check out Nano Curcumin. Thank you.

[parkie13 in reply to Despe]

I thought that you might be taking it also. A lot of people do for all kinds of health reasons.

[M1tz1]

Thank you, Parkie. I wonder if those or equivalent brands are available in South Africa. My mother had bad Alzheimer's and It would be a good idea to protect against a familial tendency. Indian people don't take supplements of curcumin, surely, so am hoping that using it daily in food will help.

[parkie13 in reply to M1tz1]

From what I read as long as you cook it in oil or some kind of a fat then it becomes bioavailable to you. Also you can use you some ground black pepper that's supposed to make available also.

[M1tz1 in reply to parkie13]

Thank you, Parkie. I do both of those things but must obviously increase the frequency of usage as I do have some forgetfulness. I'm 83. The 80s are danger years for neurodegenerative conditions. My husband had both AD and PD. I managed through the online advice of US neurologists Dale Bredesen and David Perlmutter to restore my husband's cognitive function but have become careless about my own since he died a year ago. Thank you for an important reminder. Bless you.

[parkie13 in reply to M1tz1]

Sending good thoughts your way.

[M1tz1 in reply to parkie13]

Many, many thanks. x

[slippy]

Much can be achieved with vibration healing using certain frequencys, prob best using headphones. On the subject of curcumin there is a new product called Liposomal curcumin/resveratrol that is said to absorb in a superior way. Its called Brain Power by Good Health Naturally:

Link for vibration therapy. youtube.com/watch?v=fyGmSFU...(Not working as expected?)

[Farooqji]

Although most studies had described the beneficial effects of curcumin in PD, a few contradictory reports had shown that curcumin actually exacerbated the disease, notably in a study by Ortiz-Ortiz et al., [380] which showed higher apoptosis rate in N27 mesencephalic cells after co-incubation in curcumin and paraquat. Curcumin seemed to sensitize the cells to paraquat-induced apoptosis and instead acted as pro-oxidant to greatly enhance irreversible ROS production. In another study, the exposure of N27 mesencephalic cells to curcumin induced the over-expression of LKKR2 in a time dependent manner, which thus implicating curcumin in the PD pathogenesis

ncbi.nlm.nih.gov/pmc/articl...

[parkie13 in reply to Farooqji]

Well, I give up. So what do we do?

[Hidden in reply to parkie13]

parkie13,

Something you have to consider is that in vitro studies do not always equate to in vivo studies or actual usage in humans. Curcumin in particular is notorious for this because curcumin has very poor bioavailability and does not reach similar levels in humans as it can in in vitro studies where it may be used at levels that can not be reached in the body. With curcumin, I would be more concerned with actual human studies and those studies tend to show positive results or insufficient effect due to poor bioavailability. Curcumin is one of the most studied herbs and I think there is a good reason for that!

Art

[Farooqji]

genetic test is the way to confirm compatibility

[parkie13]

If you mean the gene, I did not test positive for that one.