Anaesthesia : Hello everyone! First of all... - Cure Parkinson's

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Anaesthesia

StudioV profile image
21 Replies

Hello everyone!

First of all, I want to thank everyone in this group for being involved and sharing your life. I will start sharing more. I have been diagnosed since Jan 2015 and I’m doing really well. I’m a 55 yr old female artist. Taking c/l 25/100 three times a day plus I’m on HDT therapy, taking 1.5 gms a day, still tweaking it.

I am writing because I would like to know what precautions I should take when having anesthesia during surgery, I’m considering having a colonoscopy. Your opinions really help!

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StudioV profile image
StudioV
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Parkinson's Relief, Questions and Answers

tid1 profile image
tid1

Speak to the anesthesiologist. There are types of anesthesia they can use which minimize or eliminate the risk to Parkinson’s patients.

GymBag profile image
GymBag

Take a copy of your complete medication list qty and times you take each. Then also take 3 days worth of meds with you . If you need to stay over night in recovery or an extra day they will be handy. If you stay over they will have medicine delivery times that are different than you require so have a discussion with the nurses and doctors and pharmacy so they understand the importance of getting the meds on time. You may find that they do not have your medications in stock . Make sure you tell them BEFORE you take anything. The anesthesiologist will interview you and review the list and discuss options before the operation or procedure . Been there, done that too many times.

Good luck , relax, they know what they are doing.

I would like to mention something that has crossed my mind a few times regarding people who are preparing for a surgery in the near term. This is not a recommendation or suggestion, I'm just thinking out loud.

Many surgeries seem to go well initially and then during the recovery period an infection pops up that may be related to the surgery itself or possibly just from the hospital itself. In order to deal with the infection, testing is often done to determine if the infection is bacterial, fungal or viral, but this "lost time" doing the testing to have an idea how to treat the offending pathogen can allow that pathogen to increase its foot hold on the patient making it harder to treat, but there is not much point in just throwing a handful of antibiotics at a viral infection, so waiting for testing to be complete is useful, but in a sense, counter productive as precious time is wasted. Also consider that MRSA is active in many hospital settings and I'm sure MRSA is not alone in this respect. Colloidal silver is active against MRSA and hundreds of other pathogens.

Colloidal silver nanoparticles (AGNPs) act as a broad spectrum antibacterial, broad spectrum antiviral, an antifungal and an antiparasitic while having a very good safety profile in humans and animals. They are also synergistic with some antibiotics and antivirals. Depending on what research you read, it sounds like the AGNPs can remain active in the body for at least a few days at a minimum after you have stopped drinking them. So my thought is perhaps it would be a good thing if doctors started loading you with this yellow, golden or brown liquid at least a week before the scheduled surgery in order to boost your defenses against many of these unwanted pathogens to help your host immune system at a time when it may not being performing optimally. Consider also that after surgery, strong pain killers are typical and the norm, but these highly potent and useful pain killers tend to retard immune function right at a time when you actually need optimal immune function!

One advantage to AGNPs is that because of their broad spectrum pathogen neutralizing abilities, testing may not even be needed or they just work so well that you never even know that you were on the verge of catching some horrible bacterial, fungal or viral infection right at a time when you can least afford to! Sometimes these post surgery infections can be life threatening and wouldn't it be great to have a way to non-invasively avoid these potential post surgery infections?😊

Perhaps this could some day just become standard operating procedure for all types of surgeries and invasive procedures. Well I can dream can't I? Just think how much money this could potentially save by avoiding these serious post operative infections in the first place? AGNPs are relatively inexpensive to make while being very effective pathogen neutralizers through multiple pathways!

Okay, I am done thinking out loud and I am lowering my volume back to zero, well at least for awhile anyway!

Art

Erniediaz1018 profile image
Erniediaz1018 in reply to

Hi Art, I'm a big subscriber of colloidal silver in fact I make it myself with a small electric component I bought online. I make jar fulls and my family and myself use it up so it's been tried and tested. Since my Parkinson's diagnosis though I've been skeptical about using it for myself just because of it's metallic particles 🧐. What's your take on this?

in reply toErniediaz1018

I imagine it would depend on what type of silver you are making. I think it would matter if it is ionic or colloidal and whether it is colloidal silver or silver nanoparticles. I use a device with a built in processor that let's me know how many part per million (ppm) I am making and it can make anywhere from 10 ppm to 320 ppm or higher and it can make batch sizes from 250 ml to a liter or more. I cap anything over 20 ppm to help prevent agglomeration and I also fully reduce the batch so it turns anywhere from a baby shampoo yellow to a black coffee color depending on the ppm of the batch and the color also indicates reduction to silver nanoparticles. Before the reduction, the ionic silver is clear and colorless just like the distilled water that I start with and as it should be.

In terms of using it for yourself, I'm not sure of why the hesitancy on your part? Here is a study that you might find interesting. In this study they determined that silver nanoparticles may actually be beneficial for PD because it can lower brain inflammation and neurotoxicity by increasing the enzymes that are precursors for the generation of hydrogen sulfide (H2S), a highly potent anti-inflammatory and signaling gas produced naturally in the body, but known to be deficient in PD. Here is a link to the full study :

ncbi.nlm.nih.gov/pmc/articl...

If I had PD, I think I might try it out as long as I knew I was using good quality silver nanoparticles. Ionic silver works similarly to silver nanoparticles in terms of neutralizing pathogens, but it is much more toxic to normal human cells so I would be much less inclined to try ionic silver for PD. Good quality 20 ppm silver nanoparticles in the 12 to 20 nm size range would be my choice and this suspension should be the baby shampoo yellow color and crystal clear with no turbidity or sediment .

Art

Erniediaz1018 profile image
Erniediaz1018 in reply to

Thank you for your continued hard work of researching and sharing.

in reply toErniediaz1018

When you read the tone of that study, I got the impression they were fully expecting the opposite results because so many poorly designed studies highlight any toxic effects of silver nanoparticles (AGNPs).

Another good point to this study is that it adds confirmation to the idea that AGNPs cross the blood brain barrier which should be really great news for those who believe that PD is caused by an as yet undiscovered pathogen in the brain because AGNPs are definitely a very broad spectrum antipathogen that includes bacterial, viral, fungal and parasitic!

Art

Despe profile image
Despe in reply to

Art, another substance that you make? Please be more specific, where you buy it, recipe, etc. If it helps PwP, I will consider adding to my husband's therapy.

in reply toDespe

Despe,

No, one rodent study does not equate to an effective treatment for PD! I was just pointing that study out to Ernie to show that there was a study suggesting potential benefit. Don't go experimenting on Ray! 😅 Yes I do make and use colloidal silver nanoparticles, but I use them for other things like colds, infections, virus, mrsa, bacterial infections, cuts, burns and certain insect stings among many other things....but not PD! The setup I got was a little pricey and not practical for most people for home use. I experiment with it so for me it is worth it.

Art

Despe profile image
Despe in reply to

Art, OK, I will not experiment it on my husband. It's good info though for future application. . . You never seize to amaze me with your knowledge. Thank you!

saraoutwest profile image
saraoutwest

I recently had a 8 hr surgery with no problems. I suggest article by Simon from The Science of Parkinsons website, just search for anaesthetic . He has written an excellent article on the lastest research. (sorry don't know how to include the link.

Lionore profile image
Lionore

Colonoscopies are typically outpatient procedures, and the actual time that you will be under anesthesia is pretty brief. If you’re scheduled for an overnight stay, I would want to know why. The risk of infection is higher the longer you are hospitalized. To be safe, discuss with your neurologist and make sure that the surgeon and facility are aware of all medication, including supplements and over the counter items that you take. I would want my partner or other support person to be present the entire time that I was in surgery and recovery, not just providing transportation, and for the following 24 hours.

I had a colonoscopy ten years ago that was negative and my doctor has ordered annual stool samples as a less invasive alternative.

Despe profile image
Despe in reply toLionore

That's what I know. My husband had it about 10 years ago, and it's not invasive. No need for overnight hospital stay.

wifeofparky profile image
wifeofparky

In my area of the US, they give just a small amount of an agent like Versid that causes a twilight sleep or mild sedation. It is nothing like the anesthetics given during a more serious surgery. It is short acting and just enough to help you relax. The only problem my husband had after the procedure was difficulty in passing the air they use to inflate the colon. The pain from the trapped air was very uncomfortable and they would not let him go home until he started to pass it. Much like the pain from constipation caused by low motility with PD.

mathewc193 profile image
mathewc193

Anesthesiologists caring for patients who want deep sedation for their colonoscopy typically use a drug called propofol. ... Propofol works quickly; most patients are unconscious within five minutes.

Used as a sedative, propofol, the most popular agent used for these procedures has a narrow therapeutic window-transiting from mild sedation to deep general anesthesia rapidly. ... Second, the challenges faced by the anesthesiologist while sedating these patients are unique, both for upper GI endoscopy and colonoscopy.

Most people are awake in the recovery room immediately after an operation but remain groggy for a few hours afterward. Your body will take up to a week to completely eliminate the medicines from your system but most people will not notice much effect after about 24 hours.

So there's a case to be made for insisting that healthy people use moderate sedation rather than being put to sleep by an anesthesiologist. But there's also a risk that people who are leery of the discomfort of colonoscopy would skip the procedure, increasing their risk of colon cancer.

mathewc193 profile image
mathewc193

For one week before the procedure and 3 days after the procedure, your child should not take non-steroidal anti-inflammatory drugs (NSAID) such as aspirin, ibuprofen (Motrin® and Advil®), Naprosyn (Aleve®) or Celebrex.

Tylenol® (Acetaminophen) may be taken if needed. If you have any questions about the medicine please call the GI office at 614-722-3450.

If you take an iron supplement, it should not be taken on the day before the procedure. It may be started again the day after the procedure.

The colon will need to have all stool cleaned out for the test. The colon is difficult to check if there is stool left inside. The test may need to be redone after a more complete or longer cleanout

You will need to take laxatives for the prep.

This prep will start on the day before the test. The prep makes stools looser and more frequent. By evening of the prep day, the stools should look watery. If they do not, call the hospital at (614) 722-2000 and ask for the GI doctor on call.

You can get the items you need for the prep from your pharmacy without a prescription. If you cannot find these items, call the GI office.

Motherfather profile image
Motherfather

hi studioV i had a colonoscopy about 6 months ago it was in and out in 4 hours ,they will explain to you before you go in to have it as they get you to drink stuff you can buy from your chemist shop . all will be explained to you from the people who preform the colonoscopy its very simple you will need someone to drive you there and bring you home. im living in australia.it was my third one so no need to worry.regards.

amykp profile image
amykp

Yes, you don't really get anesthesia for a colonoscopy--you get a kind of deep sedation (usually w/propofol) that SEEMS like anesthesia to you, but is not. The worst part is the prep the day before: drink drink drink to stay hydrated!

You should be in and out of the hospital (or surgery center) very quickly. I guess there is always a chance something could happen where you'd need to stay overnight, but that something would be more likely to be a car accident on the way to the hospital than anything in the hospital. (Wear your seatbelt ;o)

On the other hand--of course disclose you have PD, well in advance to the GI doc and again to the anesthesia doc. Bring your meds, just in case.

This is from my DH, who IS an anesthesiologist. He says, yes he knows how to take particular care of folks with PD (and other conditions.) That is his JOB.

amykp profile image
amykp

A tip from me: the day before, don't load up on sugary fluids. Try clear chicken broth, and plain water.

ddmagee1 profile image
ddmagee1

I had a colonoscopy and teeth removal sedations, since I’ve had PD, and I told the Anesthesiologists about my PD each time. Everything went fine! No problem. Good luck to you.

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