Mom with PD

Here’s an update on the Mannitol. We are getting close to the end of the second month of taking it. Mom can swallow her pills and vitamins again. For so long I was having to break capsules open and put them in her food and also had to crush pills. But 2 days ago I thought I would just give it a try and put the pills in front of her with her water and now it’s no problem. I will continue to keep you posted on anymore improvements.

[jujulini]

thanks for the update. its good to hear that its helping. i started taking it about a week ago. i noticed that i feel "clearer" and "sharper". its difficult to explain. its just something i can feel. i dont think anyone else will notice.

[Sleeplessparki in reply to jujulini]

Hi jujulini how much Mannitol are you ingesting? I too started a week ago and I’m not sure if I’m feeling any better or not. I’m going to give it a month and then reassess. Have you felt any lessening in your tremor? Are you freezing up? Have you had any pain relief?

[jujulini in reply to Sleeplessparki]

sleeplessparki- im taking about 3 TBL/day (in 3 doses). after the first dose, i got cramps and alot of gas, so cut it down to a tsp. but by the 4th day, i was able to increase it with no problem. i just have a little gas.

i dont have any tremor. my symptoms (without sinemet) are bradykinesia, stiffness, weak voice, and dystonia of feet at night. i have dyskinesias from the sinemet. i havent noted any change with those symptoms yet-only on the mental/emotional plane. i just feel a little clearer and sharper.

[Hidden in reply to Sleeplessparki]

I would give it longer then that. They are saying it’s a slow process and some people it may take up to 5 Months to notice major improvements. Everyone is different. Just the little improvements I’ve seen in my Mom after 2 months tells me we are sticking with this. I have tried everything else and have spent a lot of money. This is the only thing I’ve seen work for Mom as she is in the second to the last stage of her disease. All I can say is it is a God send.

[Sleeplessparki in reply to Hidden]

Hi 1905, I will give it more time... I have to keep trying. Thanks for the input it’s appreciated

[Astra7]

Great news! it's really good to get such an objective result so you know it's really working.

[rhyspeace12]

I started my husband on Mannitol a few days ago. I have forgotten what dose one is to take.

He was more clear this morning and got worse as he got stressed during the day.

[lempa_nik in reply to rhyspeace12]

rhyspeace, You should increase the dose gradually up to a maximum of 20 grams/day, which is about 3 level tablespoons (but this may vary somewhat depending on how tightly the powder is packed.) You may conveniently give this amount in 2 divided doses, morning and evening, if you like.

[Xenos in reply to lempa_nik]

Better to stick to the CliniCrowd plan : not enough concentration and it does not work, too much and it does not work either, at least in vitro.

They tested it on murines (rats) and established a scale according to standard conversion factors from murines to human beings. For me, 69 kgs, it's 9 grams per day.

And please, do not be selfish : get registered on the CliniCrowd site and fill the questionnaire every month. It will be the only way to know about mannitol.

[jeanette2372]

Thank you for sharing that improvement.