Sinemet Plus vs Sinemet Retard

[MGP201]

When is indicated to use Sinemet Retard?

[park_bear]

That would be the Eu designation for Sinemet Controlled Release ("CR").

In my opinion: for PD, CR should always be the first choice. It provides a nice even release of levodopa, versus the immediate release("IR") which is much shorter term. That said, IR does work better for some PWP.