I was diagnosed with ra two years ago this month. My labs at that time measured an ra factor of 88 (14 and below is normal). I'm on methotexate and plaquinel. I've not had a flare since may. My questions are: why am I always in pain and periods of prednisone help to aleve some of it . 2nd; why continued pain and swelling when I'm not in a flare? I've been advised by my ra that it's time for humera. 3rd she said my labs do not show markers of inflammation. What's are the markers? I have a great ra that I can ask these questions but they don't occur to me until I've left her office. From your experiences, have any of you been given answers?