CMV PCR for blood <2.0E+2 IU/mL: Does anyone... - CLL Support

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CMV PCR for blood <2.0E+2 IU/mL

rcusher profile image
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Does anyone know what this means. It showed up on my bloodwork for the first time. I am in a clinical trial and am currently taking Idelalisib. The rest of my blood work is good.

Jack

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rcusher
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lankisterguy profile image
lankisterguyVolunteer

Hi rcusher,

-

I agree with Spark_Plug , my first thought was that your CLL expert is testing for the most common of the HHV viruses that tend to reactivate as our immune system gets weaker.

The PCR probably refers to the type of test that was done, and the part missing from your post is the normal range / cut off for that test, which is usually listed just after the result.

We also know about Shingles and EBV (mononucleosis), which are in the same family. See

en.wikipedia.org/wiki/Ortho...

SNIP:"

Nine herpesvirus types are known to primarily infect humans,[7] at least five of which are extremely widespread among most human populations, and which cause common diseases:

herpes simplex 1 and 2 (HSV-1 and HSV-2, also known as HHV-1 and HHV-2; both of which can cause orolabial and genital herpes),

varicella zoster (or HHV-3; the cause of chickenpox and shingles),

Epstein–Barr (EBV or HHV-4; implicated in several diseases, including mononucleosis and some cancers), and

human cytomegalovirus (HCMV or HHV-5). More than 90% of adults have been infected with at least one of these, and a latent form of the virus remains in almost all humans who have been infected.[8][9][10]

Other human herpesviruses are human herpesvirus 6A and 6B (HHV-6A and HHV-6B), human herpesvirus 7 (HHV-7), and

Kaposi's sarcoma-associated herpesvirus (KSHV, also known as HHV-8).[7]

In total, more than 130 herpesviruses are known,[11] some of them from mammals, birds, fish, reptiles, amphibians, and molluscs.[7] Among the animal herpesviruses are pseudorabies virus causing Aujeszky's disease in pigs, and bovine herpesvirus 1 causing bovine infectious rhinotracheitis and pustular vulvovaginitis.

-

Len

bennevisplace profile image
bennevisplace

I think it means your blood sample tested negative for IgG antibodies to the cytomegalovirus (CMV). If your other blood counts are generally OK, i.e. you're not severely immunosuppressed, that means you probably never caught the virus in your life - though by middle age most people have. It doesn't necessarily cause symptoms.

wardelab.com/test/cytomegal...

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