lumoxiti treatment

[gtforty]

I have been offered lumoxiti treatment and I have to say I am reluctant due to the listed toxicities…..anyone have treatment stories please

[lankisterguy Volunteer]

Hi gtforty,

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I am not familiar with HCL or Lumoxiti, but from the publications below, this sounds like a very complicated subject that should be discussed with your doctor in great detail and based on whether other treatments are available to you and if they are likely to be effective. Your decision probably should not be based on anecdotal opinions from other patients.

ema.europa.eu/en/documents/...

Lumoxiti as monotherapy is indicated for the treatment of adult patients with relapsed or refractory hairy cell leukaemia (HCL) after receiving at least two prior systemic therapies, including treatment with a purine nucleoside analogue (PNA)

fda.gov/media/164425/download

According to AstraZeneca’s letter to health care providers, the decision to remove Lumoxiti from the US market was related to its very low clinical uptake due to the availability of other treatment options. Complex administration and the need for toxicity prophylaxis and safety monitoring may also have contributed to its low uptake. The removal is not related to the safety or efficacy of the drug.

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Len