Flow cytometry results for mlus

[Msmilley]

Last September my cbc at my physical was all over the place. Low white count, low neutrophils, high monocytes. It continued for several months so I was referred to a hematologist. He did all of the tests including flow cytometry which showed a minimal 2% of monoclonal B cell lymphocytosis. So he called it MLUS. Monoclonol lymphocytosis of undetermined significance.

just went back this week and flow cytometry shows :no definitive B cell abnormal population identified. No abnormal T cels or myeloid cells identified. This info came through my portal I see th dr on Friday. Can MLUS just disappear? My cbc was good too. Did they mix up my blood with someone else’s. It is just weird to me that it would just go away? Anybody ever heard of this? Sorry post is so long.

[gardening-girl]

According to the US National Cancer Institute there are alternate names for the phenomenon of Monoclonal B-cell Lymphocytosis” 

MBL, atypical CLL-type

MBL, chronic lymphocytic leukemia (CLL)-type

MBL, CLL-type

MLUS Monoclonal B lymphocytosis of uncertain significance 

seer.cancer.gov/seertools/h... 

Given that, below is a quote from a paper that says that MBL/MLUS can spontaneously disappear.

“What is the clinical outcome of MBL? Given that MBL is at least 10–100 times more common than CLL, it is clear that the majority of cases do not progress to CLL. MBL may spontaneously disappear, remain stable or progress to clinically recognizable CLL or other lymphoproliferative disease (LPD).”Overview of monoclonal B-cell lymphocytosis

British Journal of Haematology    December 2007

onlinelibrary.wiley.com/doi... 

Paolo Ghia, a CLL specialist at the University Vita-Salute San Raffaele, Milan, Italy is an author on this paper.

gardening-girl

[Msmilley in reply to gardening-girl]

gardening-girl, thank you so much for that information. I couldn’t find any articles showing it could disappear. Thank you for replying!

[LeoPa]

Lucky you! Low count MBL which never progressed to High Count MBL not to mention CLL. Congrats!

[Msmilley in reply to LeoPa]

thank you LeoPa. Going to discuss results with Hematologist on Friday. Fingers crossed!

[Analeese]

Sounds like you have reason to celebrate. Blessings.

[Raleigh59]

did you have physical symptoms at your first hematology appt ?

[Msmilley in reply to Raleigh59]

Raleigh59 ,sorry I thought I responded to you that day but I obviously didn’t hit reply. I did not have any symptoms. I only had low white count high monocytes. Actually my cbc was off for about a month before I was referred out to Hematology.