4th dose - to take or not take?

[Me2AsWell]

I've had three rounds of the Pfizer COVID vaccine and my GP has kindly offered me another dose. I have negligible immunoglobulin and so am likely to generate an immune response. And I am on Aclabrutinib that is, apparently, busy suppressing my T-cells.

So ... do I take the 4th dose? Or pass? Other vaccine centres (relatively - I don't have a car) do have Moderna if I can find a way of getting there - is this a better option?

Your collective wisdom and guidance, is as ever, much appreciated.

[Pinkdark2018]

I had 3 Pfizer and the Dr at the GP hub, where I went for my booster, recommended the Moderna booster. I have no idea about my response but also I am not on any treatment. Others may be able to help you with that.

[WinJ3]

I am on imbruvica and took four Moderna vaccines. I had no response from the first two, but did develop some antibodies with the third.

I had no side effects from the first two and the fourth but had miles side effects of chills from the third.

I have no regrets about taking four.

Best wishes for you

Win

[Davidcara in reply to WinJ3]

Wondering if you know what your antibody count was after Moderna? I’m on ibrutinib too. Had three Pfizer’s with no antibodies. Scheduled for Moderna on Wednesday.

[WinJ3 in reply to Davidcara]

SARS-CoV-2 Semi-Quant Total Ab 616.0 after the third. I didn’t test yet for the fourth.

[Davidcara in reply to WinJ3]

Thanks 616, not bad

[Mtk1]

I’ve had 2 Astra zenecas, 1 Pfizer and then a Moderna for 4th, no side effects at all with 4th, I couldn’t tell you about antibodies though, I was also on acalabrutinib for 10 weeks.

[richutchens]

I just met with my Mayo Clinic doctor on Wednesday. She encouraged to get the 4th jab.

[akajeanie1]

All my doctor tests is immunoglobulin G. Are the others important as to how strong your immune system is?

[AussieNeil Administrator in reply to akajeanie1]

IgA is very important in providing protection to your respiratory, digestive and genitourinal tracts, but IgG infusions do give some protection there. At least one IgG supplier is working on providing IgA for infusion.

Neil