Ibrutinib & Thyroid

Any other CLL peers on Ibrutinib who’ve had their thyroid removed feel as though you’re experiencing (moreso) extreme fatigue, lack of stamina, dizziness, joint/bone pain?

[cllady01 Former Volunteer]

Sunny, to help others relate to your side effects and the possible source of those side effects, it would help if you would tell us when you began Ibrutinib and when you had the thyroidectomy. The following links may be old news to you. But, just in case:

I am not on Ibrutinib but I have had a thyroidectomy (1980) and the management of the amount of replacement levothyroxine has been important over the years. I see an Endocrinologist every 6 months because all medications whether prescribed or over-the-counter as well as food intake timing and specific foods can interfere with the absorption of the levothyroxine and cause fatigue among other situations.

Here are links to a site that gives pertinent information in regard to both Ibrutinib and Levothyroxine and interactions that is important to know.

drugs.com/drug-interactions...

drugs.com/drug-interactions...

Also, your post is unlocked, which means it and all replies will be on the internet. Members who do not want their personal information on the internet may hesitate to reply.

[country76]

I had my thyroid removed in 2005 due to thyroid cancer and have been taking thyroid supplements. I started Ibrutinib in 2019 the same year I was considered cured of thyroid cancer and was told I would be tested once a year instead of twice a year. 2020 I switched to Alacabrutinib due to the many side effects I was experiencing with Ibrutinib. My thyroid labs were due and the results were I was hypothyroid. Sometime in 2019 my thyroid meds stopped working. It is unclear exactly what caused it. I had so many side effects some could have been due to lack of thyroid, especially my hair thinning and breaking. I would make sure to have your thyroid labs done. It has taken until March of 2021 to get the dose corrected.