ldh: Anyone with ldh info mine went from 146 to... - CLL Support

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jdh1970 profile image
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Anyone with ldh info mine went from 146 to 208 in 30 days

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jdh1970
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AussieNeil profile image
AussieNeilPartnerAdministrator

While LDH can be an indicator of CLL tumour growth (or at far higher levels, Richter's Transformation), a higher reading can also be due to difficulties taking your blood or poor handling of your blood sample. The higher internal LDH concentration within cells broken by poor handling increases the plasma concentration. It can also jump around somewhat from test to test. I wouldn't be too concerned about your higher reading unless it continues to climb. Your results are both within the reference range - roughly 140 to 280.

Neil

johnl profile image
johnl in reply to AussieNeil

My reading have also been coming back slightly high, around 230, but they do sometimes have trouble getting my blood. I think my veins are just getting beat up.

john

HailMary-USA profile image
HailMary-USA

My LDH levels have fluctuated widely over the past 2.5 years, with no treatment.

The lab now reports this value as LD Total, with a normal reference range of 125-220 U/L.

From December 2016 to April 2019, my results have been:

586; 439; 613; 235; 385; 362; 373; 267--most recent.

Again, I have had no CLL treatment.

Best wishes to you from Mary

Hoffy profile image
Hoffy

It can bounce around. Keep watching the overall trend. Mine has bounced around but was going up as my disease got worst. It got to 1600 before treatment for me,

Be well,

Hoffy

Pippasue profile image
Pippasue in reply to Hoffy

Hello! I am coming due for labs that I have been putting off. Very nervous as my LDH was very elevated in April. How are you doing on treatment and have your LDH levels gone down with treatment ? Thanks for any info you can provide.

Hoffy profile image
Hoffy in reply to Pippasue

I was up to about 1600 then started treatment and it went down nicely to now under 200. I am on a Imbruvica plus venetoclax trial that has gone very well. See my past posts. I am on the captivate trial out of UC San Diego.

Be well,

Hoffy

Pippasue profile image
Pippasue in reply to Hoffy

Thank you for your reply. Wishing you all the best.

Mldeterm profile image
Mldeterm

My husband once nearly doubled his the day following a 20 mile training run so I can tell you LDH is very sensitive to hard exercise. It was normal the following month when he tested again.

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