I ask this question because I just had a CBC and a few other tests and did very well. Doc says I am INDOLENT. My doc was intrigued with a BCL-2 translocation and he mentioned that it might actually be helping me.(that's a switch for a change,LOL) It was on chromosome 18 and perhaps 22. Have to check in with him to discuss. But the bottom-line was that my WBCs were less than six months earlier and my ALC was up less than a point. This makes me wonder,WHAT does your body do to pick up the slack if you have very low neutrophils ? The weird thing was that everything improved for me,especially platelets this last time. But the neutrophils for me have always been very low. My RBCs got better ! Everything got better...but the neutrophils ANC was the only count that was in the toilet. Do neutrophils bounce around and does the human body have a back up system with regard to infection fighting? My IgG was 1400. But why would everything improve and the neutrophils tank?