Flow Cytometry Report and Some Math

[bkoffman]

Friends

I just posted an update on CLL flow cytometry results with some interesting math on my blog. Please double check my calculations.

Stay strong

Brian

bkoffman.blogspot.com

[Pharma]

Very happy for you Brian.

This is very encouraging for all of us.

The ibrutinib is coming soon in France.

Do you think it is preferable to associate ibrutinib with a monoclonal antibody early or wait a little or not at all?

Thank you for the good news.

[bkoffman CLL CURE Hero in reply to Pharma]

I would delay any therapy until it's needed. I like the idea of adding a mAb after being on ibrutinib for 60 days or so so that the cells are out in the blood stream for the mAB to attack. But that is all theoretical.

[Cllcanada Top Poster CURE Hero in reply to bkoffman]

A recent paper by Byrd et al... indicates that Imbruvica (ibrutinib) and rituxan used in conjunction shows signs of being antagonistic....sequential use may be the way forward... at least in ADCC cell killing...

ash.confex.com/ash/2013/web...

[nvp815]

Congratulations on the very positive results Brian. Good news for one is indeed good news for all of us!!