Nodular Liver Surface

[FlippinOut]

Has anyone had a scan that showed a nodular surface contour but it’s NOT cirrhosis? My CT scan showed nodular liver and FibroTest says F3 fibrosis (which wouldn’t be considered cirrhosis yet?) Dr wrote cirrhosis in my chart after the CT, but after the FibroTest the nurse said I have some fibrosis and scarring in my liver. Anyway my question is can a liver have nodules from advanced fibrosis or do nodules always indicate cirrhosis?

[Realy]

was the Fibro test a blood test?

[FlippinOut in reply to Realy]

Yes, they did it instead of a biopsy and because they don’t have Fibroscan equipment. It’s called FibroSure in the US and it’s calculated from the results of 6 different blood tests.

[Realy in reply to FlippinOut]

Yes I’ve had that test as well as fibroscan and ultrasound.

[FlippinOut in reply to Realy]

Did the results of your Fibroscan and FibroTest come out the same? I’m trying to decide if I need it or not and whether the CT is the ultimate diagnosis.

[Realy in reply to FlippinOut]

No but they were 6 months apart I did fibroscan and 6 months later did fibrosis blood test. I lost 45 pounds at that time and got sugar and bloods to normal. So that’s why the blood test was better.

[VeeWat in reply to FlippinOut]

Can’t you get a fibroscan in another town?

[FlippinOut in reply to VeeWat]

I’m working on that. I just need to decide between Fibroscan or MRE

[VeeWat in reply to FlippinOut]

If you want strictly staging an MRE looks at the whole liver . when my fibroscan was inconclusive my hepatologist sent me for an MRE.

[FlippinOut in reply to VeeWat]

Thank you! I think you told me that in another post which is what got me thinking about an MRE.

[VeeWat]

not many hospitals have MRE so you may have to travel to a major city.

[Belleben]

I thought nodular meant cirrohis

[ballie52]

Usually if you have a nodular liver it indicates cirrhosis!Ultrasound can show the liver surface very well and in most cases liver nodules are a result of cirrhosis.

[TruthWillSetUFree]

Have you been tested for parasites? Specifically Liver Flukes? They live inside the liver and biliary system. My husband made a simple concoction he found on You Tube made from chopped fresh garlic, lemon, honey and he added black radish which is also good for liver health. You let it ferment for a week in the fridge before eating. He started passing liver flukes and some other long 10” or 12” parasite. It was disgusting. I would imagine having these live inside the liver could cause not only scarring but also irregularities on the scan.

[Belleben in reply to TruthWillSetUFree]

What the hell is this 😯

[AyrshireK in reply to Belleben]

I don't know about the concoction being mentioned since there is medication for liver flukes BUT liver fluke is a very real condition that can cause liver problems, gallbladder and bile duct issues. It's one reason they ask if you've travelled when trying to work out your diagnosis - parasitic infection. It was considered in my hubbies case as during his frequent long hill walks he'd drink from mountain streams etc.

[Ann22987]

Flippin wondering if you had any symptoms to cause the test. Abnormal bloods? Jaundice, did they check the blood flow portal vein? Nodules usually mean cirhossis but could be advanced fibrosis. Being on the cusp and if early cirhossis still could potentially regress if lifestyle changes are made. If you want to truly stage your fibrosis MRE would be your best bet

[FlippinOut in reply to Ann22987]

Lots of symptoms, mostly fatigue and pain in upper LEFT side. Thought I had a kidney stone. But I also have metabolic syndrome and slightly elevated LFTs and was told years ago I had fatty liver. So it’s now turned into cirrhosis 😩

[Oztrax]

hi flippin out, i have exactly the same diagnosis.

elevated LFTs 2.5 times normal

fibroscan 3.5

severer fatigue

NRH could be a cause, need a biopsy to confirm

[FlippinOut in reply to Oztrax]

I haven’t had Fibroscan. The FibroTest says F3 fibrosis and the Fib4 index says F2-3 Fibrosis. I have metabolic syndrome and fatty liver so normally I’d think I have some moderate fibrosis. But the CT scan says nodular surface, likely cirrhosis.

The thing that is so confusing to me is my albumin is 4.7, my platelets are 220, AST 26 and ALT 31. Bilirubin, sodium, hemoglobin etc all normal. I look really good on paper 🤣 but I feel lousy most of the time.

Do your scans show any fibrosis? If not then you possibly do have NRH. Will you have a biopsy done?

[TruthWillSetUFree in reply to FlippinOut]

GGT 901

ALT 276

AST 210

ALP 926

My husband’s numbers…

Fibrosis Score 0.93 = F4 Cirrhosis

[ Range 0.00 - 0.21 = Normal ]

Steatosis Score 0.95 = Marked or Severe Steatosis

[ Range 0.00 - 0.30 = Normal ]

NASH Score 0.50 = F4 Borderline / Probable NASH

[ Range 0.00 - 0.25 = Normal ]

Bilirubin 3.4

[FlippinOut in reply to TruthWillSetUFree]

Those numbers are more what I’d expect to have with cirrhosis. But I guess everyone is different. What is being done for your hubby? Did he have a biopsy to confirm?

[TruthWillSetUFree in reply to FlippinOut]

He has not had a biopsy yet because we found out he has liver flukes and other parasites. Now the doctor wants to confirm he has parasites first (even though we have pictures of them) before doing anything invasive. Doctor says the tests aren’t that accurate and can give false negatives do he may have to do 3 tests to get a confirmation. We have zero doubt he has been passing them, at least 3 different kinds, and zero doubt some are liver flukes. We don’t know what stage his liver is in. He has lost a lot of weight. His biggest symptoms are itching and food intolerance… both of which are symptoms of cirrhosis AND parasites!