New medication

[JackRusselllsrule]

After recent check-up following ICD implant, Ramipril had been added to my daily medication which began on discharge in September with daily 10mg of Bisoprolol taken every morning. What time of day best to take Ramipril please, morning or evening ? My heart rate seems to fluctuate in evening, overnight, so consultant has agreed should split the 10mg morning tablet into 2 x 5mg tablets to take 8am and 8pm instead, but not sure what best time to take the additional Ramipril so it has most affect. Any ideas/suggestions/shared experience welcome please. Inevitably get nervous when heart rate goes up and down dramatically with the Defib/pacemaker to constantly think about.

[Tlyna]

Was on Ramipril for some time and had horrendous side effects from it. The shortness of breath was so bad I couldn't walk 20 feet without being doubled over trying to breath. When I stopped taking it the doctor had me double up on my Metoprolol Tartrate and the symptoms subsided for a while then came back just as bad. I don't know whether it caused it or masked the symptoms or just made the condition worse but I had to have an aortic valve replacement soon after.

• abdominal pain with or without nausea or vomiting

• allergic reactions like skin rash or hives, swelling of the hands, feet, face, lips, throat, or tongue

• dark urine

• difficulty breathing (mine very severe)

• dizzy, lightheaded or fainting spell (at times dizzy and lightheaded)

• fever or sore throat

• irregular heartbeat, chest pain (had this too and scared me badly)

• numbness or tingling in fingers or toes (already had carpal tunnel and neuropathy, don't know if it made it worse)

• pain or difficulty passing urine

• unusually weak (had this too)

• yellowing of the eyes or skin

[JackRusselllsrule in reply to Tlyna]

Thank you for response, very helpful.

[Tlyna in reply to JackRusselllsrule]

Sorry but I forgot to add that the only side effects I had were the ones I put a comment beside. The whole list is what the drug guide said were ones to notify the doctor if you had. There were s a few mild ones that weren't listed with these.

[DWizza]

I take mine in the morning but I’m only on half 1.25mg tablet and 1.25mg bisoprolol and aspirin following Nstemi heart attack and quadruple bypass July 2023.

[JackRusselllsrule in reply to DWizza]

Thanks for this, much appreciated.

[Murderfan58]

I take my 10mg of Ramipril at 5am every morning along with 3 other tablets not heart related. I have been on Ramipril for over 10 years and no side effects . I take my next tablets at 6am . Then my Flecainide at 7am and my Apixaban with my breakfast at least a hour later. Plus tablets I take at lunch time . Then Flecainide at 4-5pm and Apixaban with my dinner . Other tablets taken later .

I have PAF ,small hole in the side of my heart I was born with found out in 2020/2021 . Also born with hereditary Hyperekplexia gene mutation SLC6A5 type 3 which is a rare hereditary neurological condition diagnosed in 2022 and just been diagnosed with Osteopenia in my left hip .

But still here at 66 and have no intention of popping my clogs anytime soon.

[JackRusselllsrule in reply to Murderfan58]

Thanks, good t know.

[L8Again]

My wife is on two BP drugs. Her cardiologist said that if the morning BP drop was too much she could take one of the drugs in the early evening. He was adamant that she shouldn’t take it late evening as this could result in very low BP overnight.

[JackRusselllsrule in reply to L8Again]

That’s really helpful, thank you.

[fishonabike]

The best time to take this medication is when it suits you, as long as you take it around the same time regularly

See: bhf.org.uk/informationsuppo....

[JackRusselllsrule in reply to fishonabike]

Thank you.

[Whiteghost]

I've been taken Ramipril every evening for the last 4 years. I've never experienced any issues.

[JackRusselllsrule in reply to Whiteghost]

Thanks, reasurring to know.

[Bingo88]

Good afternoon. I am on Doxazosin 4mg 1 tablet morning and teatime and I also take 1x5mg of Ramapril at lunchtime. My meds was adjusted after I had a pacemaker fitted. Because my b.p was going too high. The easiest person to ask about when to take your meds is your chemist. Good luck. Brian

[JackRusselllsrule in reply to Bingo88]

Thank you Brian, much appreciated.