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1a2b3 profile image
19 Replies

I have been on a very low dose of beta blocker.. bisprofol for one week. Wondering if anyone experiences poor sleep quality on this medication. I am waking several times a night and then up at 5:30

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1a2b3 profile image
1a2b3
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19 Replies
Oldforge73 profile image
Oldforge73

It can be one of the side effects, I initially found this and am only on1.25mg Bisoprolol. Are you taking it in the morning as this could help. It takes many people quite some months to adjust to this drug but hopefully it will get better in time. If it doesn’t there’s other beta blockers that your physician may prescribe for you. Regards Kathleen

1a2b3 profile image
1a2b3 in reply toOldforge73

Thank you for taking the time to reply . I have only just begun taking Bisoprolol , and I’m currently taking .25 mg … one quarter of a tablet. The plan was to take that dose for one week and then go up to half a tablet the second week over the weekend. I was having some issues with some chest pain and was advised to just stay on the lower dose until I see the cardiologist on November 8 I did go to the ER and check was checked out and everything was fine. No issues with my heart so not sure what that was all about. I did Google side effects and one thing that I did read, and I’m not sure how accurate it is, is that this particular drug can deplete your body of melatonin, making it difficult to sleep and causing insomnia… The suggestion was to take melatonin . I have taken melatonin in the past, but I didn’t always love the way I felt the next day. I always felt a little bit out of it for a while, so I’m not sure if that’s going to be the answer when I’m already tired. Seems we take a pill to fix one thing, but then the fix creates another problem.

Skiffrower profile image
Skiffrower in reply to1a2b3

It took about 6 weeks after op for me to get my body and Bisoprolol tolerated. My experience was it helped to make sure I'd eaten before taking the dose (1.25mg) . As I'd had a major op my sleep patterns were shot anyway. Good luck on 8th Nov.

1a2b3 profile image
1a2b3 in reply toSkiffrower

Thank you !

Oldforge73 profile image
Oldforge73 in reply to1a2b3

The reduction in melatonin is indeed a common factor when on Bisoprolol along with the adaption our body needs to get used to a beta blocker. It took me so long I nearly gave up but as I have AFib realised I needed some meds. Even after a year I can still have wakeful nights but not so often now. I guess I am as used to this drug as I am ever going to be, hopefully over time the side effects will improve. Regards Kathleen

1a2b3 profile image
1a2b3 in reply toOldforge73

thank you . I’m glad you found things settled a bit . I haven’t had great sleep since menopause but I knew that pattern. This is a bit different so I guess we’ll just wait and see how my body adjusts and hopefully I don’t have to do too much. I am currently only on 25 mg,the lowest there is.

AmatureKnitter profile image
AmatureKnitter

When I asked about this problem a cardiac nurse told me it messes with your melatonin production. I now take it *immediately* before going to sleep, if I fall asleep quickly then I'm usually OK. If, for any reason I don't fall asleep then I'm stuffed - that night is a write-off. I stick to a bedtime routine, take valerian and magnesium an hour before, read a book (not screen) until I'm nodding, take the Bisoprolol and turn out the light.

Also I found it got better after a few weeks but worsened again with each increase in dose. It reaches peak serum levels at 4 hours and has a 10 hour half-life. I found over 2.5mg I couldn't take it in the morning as there was enough hanging around to keep me awake at bedtime. It's an awful feeling "wired but tired".

1a2b3 profile image
1a2b3 in reply toAmatureKnitter

thank you for your reply… I was taking mine in the morning and I switched to evening. I do take magnesium every night. I wondered about taking a low-dose of melatonin to see if that helps but I just I don’t want to have that hangover feeling the next day . I do not nap in the daytime as I find that interrupts my sleep. I am usually very, very tired at bedtime. I’m falling asleep watching a show . Falling asleep is not the problem, it’s staying asleep and not waking up several times.

1a2b3 profile image
1a2b3 in reply toAmatureKnitter

one thing I meant to ask… Did they recommend taking a low dose of melatonin?

AmatureKnitter profile image
AmatureKnitter in reply to1a2b3

No. And it didn't dawn on me too ask.

Jedi14 profile image
Jedi14

Ever since my heart troubles, sleep has been there but in patches. So I try and get a "Total " of sleep hours, but not all at once!

1a2b3 profile image
1a2b3 in reply toJedi14

I haven’t had good long sleeps since menopause but this has been tough . Hopefully it levels out once my body adjusts . Thank you

Breesha profile image
Breesha

Bisopropol is my life saver , you lack of sleep perhaps because you were worried about Biso

1a2b3 profile image
1a2b3 in reply toBreesha

I wasn’t worried as I hoped it was going to help with possible micro vascular pain . As we know everyone responds differently to meds.

EdtheDead profile image
EdtheDead

I had issues at the beginning but everything settled quickly. I'm on 3.75mg and found that splitting the dosage to 1.25mg 3 times a day really helped.

1a2b3 profile image
1a2b3 in reply toEdtheDead

Thank you !

Louisthe6 profile image
Louisthe6

Yes I have been on Bisoprolol for over 2 years now and still cannot sleep properly. I have been using a low dose mirtazapine recently and that helps a little.

Best regards

1a2b3 profile image
1a2b3 in reply toLouisthe6

Thank you for your reply … I have read to try melatonin but have also read this can lower BP and even on the lowest dose of Bisoprolol , my BP has become very low. I will investigate mirtazapine

1a2b3 profile image
1a2b3 in reply toLouisthe6

I see mirtazapine is an anti depressant … I was prescribed trazadone before I started with Bisoprolol and didn’t like the hangover effect I felt fur the better part of the day .

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