Nilembdo: I have been using Repatha for... - British Heart Fou...

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Nilembdo

Scaramazza profile image
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I have been using Repatha for over a year to reduce my cholesterol which is due to some genetic mutations. It is working well but my consultant suggested integrating this treatment with NILEMBDO for a month at least and see if I am ok with it. I read that this medication may increase uric acids and would like to know to what extent this is a risk and have some guideline for optimum diet as on the net I get information for those who already have gout. Thanks

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Scaramazza
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Blearyeyed profile image
Blearyeyed

I have read some good things about bempedoic acid , also known as Nilembdo , in treating Hyperlipidemia and Cholesterol.As you say , at the moment you are taking the Repatha , which if I remember rightly is an injection and is quite costly which means less people are getting the opportunity to get the benefits of it.

According to a lot of specialists , Bempedoic Acid , works very successfully and is a lot cheaper which means it will open the doors for treatment to many with certain cholesterol and lipid conditions whom can't take statins , or can't control the condition with statins alone.

Is there plan to keep you on both treatments or finally decide to taper you off Repatha and replace it with Nilembdo ?

The potential of increased Uric Acid can be an issue with many conditions , so helping to prevent that by making some changes in your diet is a good idea.

The diet you could loosely follow would be the diet type which does help to improve conditions like Gout. It's called the Low Purine Diet.

You would not need to follow it as strictly as people would whom already have a Uric Acid problem as it can be quite restrictive on top of other diet changes you will have made to improve your cardiac health and cholesterol.

The most useful changes are to restrict sugar intake , including syrups, and definitely avoid artificial sweeteners.

Alcohol is better avoided as well.

Offal and Game meats , many shellfish, some oily fish like herring , tuna , and anchovies are also better off the food list.

You are probably already reducing your red and processed meat intake , but if you aren't, it's better to limit this too.

And as with most healthy diets you should avoid highly processed foods and ready meals.

A wide variety of fruit and vegetables are encouraged.

Eggs are considered to be a good source of protein on a low purine diet and the yolk contains good cholesterol. They are usually ok on a diet with less saturated fat from red meats ;but you can choose to eat one yolk to 2-3 egg whites if you prefer.

Dairy products , grains and pulses are also good.

As is Chicken ,Turkey Breast meat , although you are better to limit dark turkey meat.

Some people take Omega 3 supplements after a meal to compensate for the reduced amount of oily fish in their diet.

Interestingly , coffee can be beneficial but only if it does not cause you any cardiac symptoms with the condition you already have.

The risk of Uric Acid is 1-100 approximately but this would decrease if you've made diet changes. You might benefit by eating foods containing iron or having your iron level checked after the first month because some people can become anaemic on cholesterol and lipid medications.

It can cause some muscle aches but that is less common than it is on other cholesterol lowering medications like statins or Repatha so if you feel ok on the medications you are having now muscle soreness shouldn't be a problem.

This is a pretty new medication , and most people on the forum probably won't have heard about it or know about Repatha either so I am sure forum members would be really thankful if you wrote some posts about taking these drugs and what your experience is on Nilembdo.

Hope it works for you , it's all trial and error isn't it but it's worth trying things to see if they will give you the results you want, take care , Bee

Scaramazza profile image
Scaramazza in reply toBlearyeyed

Thank you for your reply and comments. I will continue with Repatha which i tolerate very well and lowered my cholesterol . However, my consultant asked me to try Nilebdo initially for one month and possibly in the future too in order to lower my cholesterol even more in conjunction with Repatha. Repatha is very effective and not a single side effect as far as i am concerned. Will keep you posted about Nilebdo.

Happyrosie profile image
Happyrosie

along with the very helpful post from Blearyeyed. You asked the extent of the risk. Your pharmacist might have some insight into this.

Dollywow1999 profile image
Dollywow1999

Check out videos by semiretired Bob.......he went carnivore for o ver 16 months now and he got rid almost 100 percent of his gout and he coukdnt even stand fir 15 minutes nor walk much at all now he walks a LOT ....eating meat!!!! Check him out

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