Entresto! Side effects? Length of time on? Improvements? Whats your experience?

So i have been taking entresto for 2 years now and on the middle dose. I was taken to hospital with heart failure and suspected heart attack with trophin levels being extremely high. After a rough 10 days in ICU i had eventually picked up enough to get a MRI scan. My ejection fraction rate was 12%. I was in AFib.

After couple rough months of being on meds with nothing working (betas, apixiban, clopidogrel, eperlenone) i had switched over to entresto. Hailed a miracle drug. Within days i had seen my hands finally warm up as they were constantly freezing cold. I noticed ever slight improvements.

After the cardioversion i was back to normal rythum. And more improvements seen over the months. I got a scan and my ejection fraction is now around 45%.

I do notice sides after taking the entresto tablet pretty much within half hour... Fatigue, drowsiness/brain fog, sometimes chest discomfort, sometimes aniexity.

I am on the middle dose and i have just told my cardiologist that i split the morning dose in half due to the bad sides and it prettt much works out alright.

Whats your experiences on Entresto, good or bad? Any sides? Has anyone recovered to a point where they could drop taking this med and others?

[Prada47]

Hello I have been on Entresto for a couple of years now and it's hard to say if it has improved my HF symptoms. I know my EF has reduced slightly from 44% to 38% (not to bad )

The reason I can't fully explain is in May I had my already bypassed LAD opened up as my Cardiologist though it would help blood supply to an that area of my heart, and maybe reduce being so breathless. I do still get breathless but recovery is much quicker. That's difficult to explain but after a shower it would take quite a while to recover my breathing, now it is much quicker.

So was it the Entresto or the Forxiga ( Dapa ) or the opening of my bypassed LAD. My Heart Failure Nurse just says they all contribute to keeping me going, you may not be getting better but these have certainly arrested the decline.

At 75 I do feel reasonably good and long may it continue I see people in a much worse situation than I am but hey ho another Christmas has come around and long may they continue.

Merry Christmas Hope you can understand my post.

Regards

[RufusScamp]

I have been on the highest dose for a couple of years, and my EF has improved from 20% to 60%. I am hoping this will enable me to reduce some of my other meds, but am finding it difficult to find out!

[Hidden in reply to RufusScamp]

Excellent news! I'm due a scan next week and hoping for some good news.