clopidogrel and supplements

[BG63]

can you take turmeric with clopidogrel?

[MichaelJH Heart Star]

Hello and welcome to the forum! I would strongly advise against it as Tumeric enhances the action of Clopidogrel which could lead to a bleed be it a nose/glum bleed or an internal bleed. Anybody on any form of medication should run any supplement past a medical professional before taking it!

[Hidden in reply to MichaelJH]

Totally agree with your answer, people don't realise that a lot of damage can be done with so called natural medication mixing and interacting with pharmaceutical ones.

Also if you get the ok for taking supplements { pharmacist is also a good goto for asking about interactions } take the time to find out about them, the market is flooded with substandard supplements and although the ingredient name maybe natural , how they extract it and what binders/packers etc they use, in a lot of cases, are not.

Hope you are as well Michael as you can be

[MichaelJH Heart Star in reply to Hidden]

Suffering phantom pain - see my upcoming post!

[BG63]

Thank you - I've been taking clopidogrel for 7 years and had no idea that I would need to check out supplements etc. I know I should read the leaflet with the tiny writing but I don't have super duper vision. I've also heard that I should be careful with some of my favourite foods; asparagus, broccoli, cauliflower and others. Has anyone any advice in that regard?

[MichaelJH Heart Star in reply to BG63]

You can enjoy your vegetables with Clopidogrel. There are issues with Warfarin, and I think some bar stool experts and Daily Fail readers mix these up despite Clopidogrel being an antiplatelet and Warfarin an anticoagulant. As in all things moderation is the key.

Youn should always read the PIL (patient information leaflet) as there may be specific interactions. For instance, I had to avoid dairy for two weeks post revision surgery because of the antibiotics I was prescribed. They also had some unpleasant side effects, but they did the job required.

[Digger0 in reply to BG63]

I usually look the PIL up on line if I can't read them! I usually use the BNF site.

[Zbignieva]

There are also issues with tumeric and statins. I think there are numerous drug interactions.

sps.nhs.uk/articles/advisin...

[Milkfairy Heart Star in reply to Zbignieva]

Biotin another common supplement can affect troponin blood level test results.

tctmd.com/news/biotin-suppl...

[Zbignieva in reply to Milkfairy]

Any company that use biotin, for example Roche, have re formulated their reagents so that the antibody-antigen interaction is no longer streptavidin-biotin. It was the first one they did after the issue was discovered.

They are going through all of their reagents and replacing these two substances, I think this issue may have been specific to Roche, which generally is one of the best immunoassay analyser.

Every lab that uses Roche will be aware of this as we have to verify and validate each new formulation of an assay, as well as do all sorts of IT changes.

So while biotin does not impact your heart to release or suppress more troponin T, if you did had a heart attack before this change and were taking a huge dose of biotin, it wouldn’t have detected the troponin.

This can still happen for A LOT of tests right now, including tumour markers, so taking hair and nail supplements is not recommended.

[Milkfairy Heart Star in reply to Zbignieva]

That's the issue taking supplements can alter important blood test results.

[Zbignieva in reply to Milkfairy]

I found a great review paper, basically, don’t take huge doses of biotin, or stop 48 h before a blood test, otherwise some of your results may be inaccurate.

It is Roche, Vitrous, Immunolite, and Beckman-Coulter that use streptavidin-biotin on analysers, but this may be used on manual test as well.

ncbi.nlm.nih.gov/pmc/articl...

[Qualipop in reply to Zbignieva]

The only one I knew about was that grapefruit is a complete NO with statins.

[BG63]

that is so helpful - thank you

[Breesha]

who knew that Licorice ( I love it ) is banned with DIGOXIN , my pharmacist

Stopped me buying delicious soft Licorice ……meany