Entresto and tiredness!

[coop61]

Hi I am just going on to my 9th day on ENTRESTO can anyone tell me did it cause tiredness and does it stop? If so how long I know everyone is different and we are not doctors thanks in advance

[RufusScamp]

I have been on the maximum dose of Entresto for about a year, with no obvious side-effects. I get tired mid afternoon, but did before, and blame (rightly or wrongly) the bisoprolol.There has been a great improvement in my condition however. I hope the same is true for you.

[Pewib in reply to RufusScamp]

Hi, I’ve been on Entresto for 18 months with no tiredness or side effects. It’s been so much better than Ramipril and I’ve noticed real improvements in my symptoms. As you say everyone is different. If you are feeling a bit tired go with it, have a siesta if you can, I think the benefits of Entresto far out way the milder side effects.

[coop61 in reply to RufusScamp]

Just on it under 2 weeks ! So not given it much time but I do take bisoprolol also probably the cocktail of heart and blood pressure meds! So glad to hear you are feeling much better on it! 👍🏻

[Invermill]

Hi coop61, I’ve been on the highest dose for six years and haven’t noticed any issues. I hope you feel better soon. Regards

[coop61 in reply to Invermill]

Brilliant ! I do take other meds also so hopefully it will settle down just started on medium dose! Glad to hear no bad effects for you! 👍🏻

[am1875 in reply to Invermill]

Good morning over here Invermill. Splendid to hear your lengthy experience with Entresto. Mind if I ask how its affected EF. Cheers!

[Invermill in reply to am1875]

Hi am1875I'm sorry I haven't got a clue as I've never been checked for EF since taking entresto.

[colwynn66]

Hi I've been on Entresto just over 4 years. I can say it's working well for me you need to give it time. You can just get tired from your condition but you will see an improvement in time.iam back driving hgv now.hope you fell better soon.

[coop61 in reply to colwynn66]

Waw! Well done you! Just on not even two weeks I do take other heart meds so maybe the mixture! Glad to hear it’s working well for soo many people! 👍🏻

[depy]

I have been on the minimum dose of Entresto since March. I felt tired in the beginning, then after a while I got better. Now I feel knackered again but I reckon it is the spironolactone that I started recently. Possibly needs some time to get the body used to it.

[coop61 in reply to depy]

Oh don’t say that I have to get bloods checked next week then they want me to start on that one also! 🙈

[am1875 in reply to depy]

Hi. I was on the middle dose but today was put on the lower dose. Since you’ve been on it, has your ejection fraction increased, and do you have more energy? Thanks in advance for your feedback.

[Frank1803]

Just been on it for a few weeks ....I get tired late afternoon....but apart from that I am ok....been told there are good benefits in taking this drug.

[coop61 in reply to Frank1803]

That’s like me under two weeks! 🤞 all good for us all! 👍🏻

[Archiebear1]

I’m on max dose of Entresto since March and it’s really helping with breathlessness I still have chronic fatigue I will sleep til 3pm don’t know if that will ever go I’ve been told I’ve got severe heart failure but since being on Entresto & Dapaglifozin Ive noticed an improvement

[coop61 in reply to Archiebear1]

Brilliant ! Hopefully the improvements keep coming for you and all of us! 👍🏻

[Hoocher]

I was on Entresto for 3 months and was continually light headed and tired. I was put back on ramipril and within a week I was back to walking 5 to 10km without any issues and no light-headedness

[coop61 in reply to Hoocher]

Yes I think I felt better on ramipril but will definitely give it a good go! 👍🏻

[am1875 in reply to coop61]

Hi. I wonder if the health providers are caught up in the moment and switching everyone to Entresto, which may or may not be as good at the current medication. I’ve been feeling good for yrs. and just given Entresto a week ago. I’ll watch closely see how it does. Cheers

[am1875 in reply to Hoocher]

Hi. Is the Ramipril still working for you? Thanks.

[Hoocher in reply to am1875]

Hi, yes it is. 3.5 yrs down the line and I've been fine . I've got an appointment to see the cardiologist in 2 weeks so will speak to him. My own GP did speak to him about 9 months ago to ask if I should have another try on Entresto and he said no. I'm hoping to find out why he said no when I go. I'm absolutely fine on Ramipril, I was more curious to see if Entresto would still have the same effect on me, now my body had become accustomed to the other meds.

[am1875 in reply to Hoocher]

Makes sense.