Essentially DAPT is typically continued for 6 or 12 months in people who have had a stent fitted, who then revert to aspirin monotherapy. This trial shows that patients with simple stents (and no heart attack) did not face additional risk after stopping their secondary anti-platelet after 1 month. It's typically only people at high risk of bleeding that do this currently.
Clopidogrel caused me all sorts of problems and I weened myself off it after 6 months (against medical advice) It's a shame this study wasn't out 12 months earlier as it could have saved me a lot of pain.
As always, read with interest but don't change your meds without discussing it with your doctor. It'll be interesting to see if NICE react to this.
Why ? USA cardiologist get paid a lot of dollars 💸 to write this stuff. And you will probably never hear about it again. Look at the numbers. Very small
I thought ~3000 participants was fairly significant given the difficulty in screening suitable participants. Your point about financial influence is noted and that's why it is important to read more than just the conclusion, but in this instance, I doubt big pharma is financing a study whose results suggest less drugs could be better.
I'm always interested in developments in this area, and this one could save lives with less bleeding incidents. I'd consider it significant.
Sorry I based my response on figures confirmed in 2020
As of 2018, 30.3 million U.S. adults were diagnosed with heart disease. Every year, about 647,000 Americans die from heart disease, making it the leading cause of death in the United States. Heart disease causes 1 out of every 4 deaths .sept 2020
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