The cholesterol lowering drug, Inclisiran, that has been undergoing trials for some years has been approved for use by the NHS. It is delivered by twice yearly injection
What puzzles me is that the article that it will be prescribed to people who have already had a heart attack or stroke .. I would have thought it could be appropriate for those who have had stents or a bypass for other reasons, those who have needed any type of procedure for PAD (Peripheral Arterial Disease) and anyone with elevated cholesterol who is genuinely intolerant to all oral cholesterol lowering drugs.
Written by
MichaelJH
Heart Star
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Yes I am sure cost will restrict its use to those who really need it. It will not be an alternative to those who keep forgetting to take their statin! After all it is £1,000s per annum when stains are pence per day!
Inclisiran was discussed in quite a bit of detail during the BHF's on-line presentation last week. The way they positioned it this new drug was chiefly for people with Familial Hypercholesterolaemia, the genetically inherited condition that results in very high LDL cholesterol levels. Those people, and in particular patients who had inherited the PCSK9 gene that causes Familial Hypercholesterolaemia from both parents rather than just one, would be offered both statins and a twice yearly Inclisiran injection.
So I could be one of those offered it then. I have familial hypercholesterolemia. Diagnosed 9 years ago. Didn’t stop me having a heart attack though. So hopefully this new drug will help people.
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Unblocking Mild Atherosclerosis with Meds
Statins 
Inclisiran
