Ompreloze and side effects: I am on a... - Asthma UK communi...

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Ompreloze and side effects

elanaoali
elanaoali
16 Replies

I am on a two month trial of ompreloze 40mg twice a day. This is week 6. While my symptoms of sickness of have gone, I still have a sore throat off and on during the day but the salty taste in my mouth has decreased.

So I think it's been a success. There is only one thing I have got constipated. So I bought lactose solution from the pharmacy which is helping a bit. I have a good healthy diet and drink plenty of water. Anyone else got any more solutions?

16 Replies
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HungryHufflepuff

It’s really good to know it’s working for you. Everything seems to have side effects of one kind or another though 😞

Tropicana do a whole fruit juice which supposedly contains 50% more fibre than other juice. Otherwise prune juice if you like it? Hoping things continue to improve for you 😊

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elanaoali

Thanks Hungryhuff but I unable to have orange,apple or prune juice. I have a condition of the bladder which means juice is out.

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HungryHufflepuff

I'm sorry to know that. Can you eat soups? Green soup with cabbage, Brussels sprouts, spinach etc would be fairly high in fibre. And maybe this is just something I've convinced myself is true but, chocolate! Good quality dark chocolate works too. I hope you'll find something that helps.

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elanaoali

Thanks for the further suggestions. I am sorry for not mentioning my long list of forbidden foods. Nonething acidic, no process foods ie sausages, no caffeine (chocolate is out), no yogurts but can eat veg til it comes out of my ears. I can eat dates and certain kinds of nuts(high in fibre I think)

Maybe I could try soup it would have to be homemade without tomatoes.

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HungryHufflepuff

This must be quite tricky for you. Home made soup is good, or vegetable casserole, you could add in beans and lentils. 🍲

Very best wishes to you 😊

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elanaoali

Yes it can be tricky but gives you a very healthy diet. Thankyou for your kind wishes

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Ghoulette

I'm sorry that you have developed this side effect. Lactulose can be very good. It is one of the more gentle formulations on the market. I'm not sure what dose you are on, but maybe that could be increased? There are stronger alternatives available which, although can be bought over the counter, if you haven't used them before, maybe try them under the supervision of your GP?

There are products called Movicol, Cosmo-col, laxido, etc. They are all powder dissolvable in water. Like lactulose, they rely on having adequate water intake to make sure they work correctly. It is important to drink plenty of water each day. If possible, you could try gentle exercise too.

Hope this helps x

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elanaoali
elanaoali
in reply to Ghoulette

Thankyou for your advice. I started using it about 10 days ago. I bought on advice I got from a pharmacy. I started at 15ml once a day. Now move to 15ml twice a day. I am trying to drink plenty of fluids.

I have an appointment in 10 days time to review the medication.

If I still struggle I will of course mention it.

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elanaoali
elanaoali
in reply to elanaoali

Had my appointment to review my ompreloze trial of two months at 40mg twice a day. GP deem it a great success.

Still have sore throat but not sure it's due to either a remance of a cold last week or oral thrush. So I waiting to see if it resolves itself.

So plan going forward is to reduce to 20mg twice a day instead of 40mg twice a day. I started doing this two days ago for a month then maybe down to 20mg once a day ("If feeling brave" doctors words)

The GP said I have complete freedom to increase back up if acid reflux comes back. I was reassured that being on ompreloze long term even at 40mg twice a day is safe. I had a concern about my bone density could be effected by this drug. Doctor didn't think it was a problem. Advise instead vitamin D tablets which I am quite wiling to do.

Still sticking to acid reflux diet but have fallen off the wagon a few times. Fatty foods ie. Chipshop chips ☹️ and fatty meat (lamb) really bad indigestion which no glavison will touch.

So adding another repeat prescription to my list and as my mum says if you shoke me I'll rattle!?

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HungryHufflepuff

It’s great news this seems to be working so well for you. Hopefully it all continues to be so good with the reduced dose.

I’ve started taking vitamin D3 + K2 because the K2 apparently helps better absorption.

I hope you get better from your sore throat very soon and it’s nothing too worrisome. 🤞

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elanaoali

Thanks Hungryhuff. Interesting what you said about vitamins.

I take you rattle too😉

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elanaoali
elanaoali
in reply to elanaoali

After reducing my dose down to 20mg twice a day from the 40mg twice a day the symptoms of throat throat is back.

I rang my doctor's for advice (last Friday) and the duty doctors suggested I could try 20mg AM and 40mg PM. So did this and it hasn't worked.

So I going back up to 40mg twice a day from today and have a doctors appointment next Monday.

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HungryHufflepuff

How disappointing that the lower doses don’t work. Are things starting to improve again now that you’ve increased the dose back up to 40mg? I hope things start to get better again soon 🤞

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elanaoali

Thanks for your kind wishes. I am not giving up yet. I only started going back up with tonight's dose. I expect it will get better quite quickly.

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elanaoali
elanaoali
in reply to elanaoali

After increasing my dose of ompreloze back up to 40mg twice a day my symptoms settled down.

I then went back to the doctors (two weeks ago) for

a review of my medication. I told the doctors about what happened when I reduced the dose. His advice was to stay at 40mg then try and reduce again to 20mg am and 40mg in two weeks time.

Times up on Monday so I am hoping that my body will tolerate a reduction of my dose.

The sore throat turned out to be laryngitis and is alot better.

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HungryHufflepuff

I'm glad your sore throat is better and was unrelated to the reduction of ompreloze. That's one less thing to worry about I suppose. I hope your next reduction of the dose goes better this time 🤞

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