People with cancer who exercise generally have a better prognosis than inactive patients. Now, researchers at Karolinska Institutet in Sweden have found a likely explanation of why exercise helps slow down cancer growth in mice: Physical activity changes the metabolism of the immune system’s cytotoxic T cells and thereby improves their ability to attack cancer cells. The study is published in the journal eLife.
“The biology behind the positive effects of exercise can provide new insights into how the body maintains health as well as help us design and improve treatments against cancer,” says Randall Johnson, professor at the Department of Cell and Molecular Biology, Karolinska Institutet, and the study’s corresponding author.
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Elife sciences. Research paper: (click on the various sections to expand the text)
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