An in-depth analysis of the genome sequence of coronavirus circulating in Norfolk, UK by researchers at the Quadram Institute and University of East Anglia has mapped the spread of the virus, identified hidden outbreaks and provided insights into the effectiveness of interventions to stop its spread.
Over 1,500 COVID-19 genomes representing 42% of positive cases during the first wave of infections were sequenced for this study. Only Australia, Spain, India and the U.S. have sequenced more genomes than have been sequenced in Norfolk.
....................This study confirms and adds to our knowledge about this novel coronavirus. The virus has a stable, low genetic mutation rate. A mutation in the spike protein, linked to increased transmission of the virus, came to dominate in Norfolk during the timeline of the study, something that is reflected globally. Also, there was no evidence of reinfection within the region, adding to the evidence that reinfection remains rare, at least for now.
