How the coronavirus could be prevented from invading a host cell.

[2greys]

How might the novel coronavirus be prevented from entering a host cell in an effort to thwart infection? A team of biomedical scientists has made a discovery that points to a solution.

The scientists, led by Maurizio Pellecchia in the School of Medicine at the University of California, Riverside, report in the journal Molecules that two proteases — enzymes that break down proteins — located on the surface of host cells and responsible for processing viral entry could be inhibited. Such protease inhibition would prevent SARS-CoV2, the coronavirus responsible for COVID-19, from invading the host cell.

The research is featured as the cover story of the journal (Volume 25, Issue 10).

news.ucr.edu/articles/2020/...

[Ergendl]

Presumably though, those proteases are a part of the host cells for a reason. Still, great to find the scientists finding another method of defence. Hopefully without too many side-effects.

[Jaybird19]

There is going to be an explosion of knowledge after this episode of covid19.

Do you know anything about Heiq basically using silver as antiviral?. I tried to email and this was blocked!Never had a contact address blocked before.

Hope you are both progressing well.0

[2greys in reply to Jaybird19]

I am slowly getting there, it is like 6 steps forward and then 5 steps back again. I am trying to get fit enough to have a CT Scan at the beginning of July. It is 500 metre walk and a set of stairs from the main entrance to Oncology Imaging. A daunting prospect at the moment.

[Jaybird19 in reply to 2greys]

Is there no lift.?They surely have a lift for patients somewhere. I was put in a wheel chair and pushed around much to my disgust at Salford . Had no option although i could walk . Are you trying to be too independent. ? It is very hard to admit.

[2greys in reply to Jaybird19]

I will not use them, a cramped compartment, shared with others who could be infectious or carriers of all sorts of germs, the stairs is always quicker anyway.

[Jaybird19 in reply to 2greys]

Yes I. Understand but how will you be getting to the hospital itself? There are hospital volunteers to drive you there, better than public transport. I have to go at end of june unless they cancel it but not so important and not happy !

[2greys in reply to Jaybird19]

Not sure yet, I am waiting for the appointment letter first. If my son is not working then he will take me. If not then I will have see if I can get hospital transport, failing that then it will be £40 in taxis. I will not use public transport that is for sure.

[Jaybird19 in reply to 2greys]

Agreed about public transport . I used the volunteer transport in my area last year and although these volunteers do lots of journeys they are probably better than taxis and they helped at the hospital too. I dont know how much you know about this but i did have difficulty at first getting contact number. I believe there are a number of these around the country some run through charities like a Age UK and Red Cross. Some are free and some there is a mileage charge

Good luck