An enormous library of products derived from more than ten thousand fungi could help us find new drugs. Researchers from the group of Jeroen den Hertog at the Hubrecht Institute, in collaboration with researchers from the Westerdijk Institute and Utrecht University, have set up this library and screened it for biologically active compounds. They tested the biological activity of these fungal products first using zebrafish embryos. The researchers chose to use zebrafish embryos, because it allows the analysis of effects on many cell types at the same time, in a working body, and because zebrafish are physiologically very similar to humans. They have already found various known compounds, among which the cholesterol lowering drug lovastatin. The library of fungal products offers ample opportunity to search for new drugs. The results of this research were published on the 26th of November in the scientific journal Scientific Reports.
Using fungi to search for medical drugs. - Lung Conditions C...
Using fungi to search for medical drugs.
Written by
2greys
To view profiles and participate in discussions please or .
Read more about...
Not what you're looking for?
You may also like...
Fewer fungi types in lungs linked to worse disease in acute respiratory distress syndrome.
Many COVID-19 patients develop acute respiratory distress syndrome (ARDS), a life-threatening...
Anti-COVID-19 nasal spray 'ready for use in humans'.
A nasal spray that can provide effective protection against the COVID-19 virus has been developed...
Immunity to COVID-19 is probably higher than tests have shown.
New research from Karolinska Institutet and Karolinska University Hospital shows that many people...
Researchers show that certain antibiotics can prevent the entry of SARS-CoV-2 into cells.
The Drug Design and Molecular Topology Unit group of the University of Valencia has shown that...
Makers/Suppliers of model kit glues and paints with low odour/irritant qualities?
I am looking for craft glues, paints and primers which are suitable for use with 'Airfix' type kits...