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See Annex D and E
Can anyone translate EmmaF91 perhaps??
Rule 3: Respiratory
This rule is to identify patients with severe asthma Patients or severe Chronic Obstructive Pulmonary Disease (COPD)
Identification of patients with severe asthma was defined as taking regular or continuous courses of prednisolone, alongside ICD-10 coding.
The usual medicines prescribed for patients with asthma are classified under BNF sections 3.1, 3.2 and 3.3. Many of the medicines within these BNF sections are also prescribed for patients with Chronic Obstructive Pulmonary Disease (COPD).
Since PCPM data does not include indication for prescribing, it is not possible to differentiate all prescribing within BNF 3.1 and 3.2 between asthma and COPD.
Patients likely to have severe asthma were identified, using medicines data, by the following methodology:
a. Patients with asthma were identified as being prescribed Long acting beta2-agonist (LABA) as either a LABA or in combination with an inhaled corticosteroid (LABA/ICS) OR prescriptions for a leukotriene receptor antagonist (e.g. monteluekast).
Sub paragaphBNF code
Leukotriene Receptor Antagonists030302
A list of LABA and LABA/ICS medicines (presentations) used in the analysis is detailed in annex D. Formulations indicated only for COPD were excluded (Indacterol; Olodaterol).
b. From the above list of patients, those who had been dispensed 4 or more prescriptions for prednisolone between July 2019 and December 2019 were identified and considered to have severe asthma.
Chemical substanceBNF code
Prednisolone0603020T0
Due to time constraints more detailed analysis of the quantities of prednisolone per prescription (such as number of tablets) was not possible.
Whilst PCPM data does not include medicines prescribed and supplied by secondary care there can be a reasonable assumption that the majority of the management of asthma and COPD is undertaken in primary care via FP10 prescriptions.
In order to identify regular or continuous prescribing of prednisolone (defined as 4 or more prescriptions), analysis of the full 6 months data was necessary. Patients who commenced regular or continuous prednisolone recently (for example, October onwards) may not be included.
Because of the method of identifying patients with asthma, the data will include patients who have COPD and have also received 4 or more prescriptions for prednisolone. However, removing the patients identified in COPD analysis will have reduced the number (see below).
Patients who were likely to have severe COPD were identified, using medicines data, by
a. prescriptions for a Long Acting Beta Agonist (LABA) and a Long Acting Muscarinic Agonist (LAMA) and an inhaled corticosteroid (ICS) in either November and/or December 2019.
NB: prescribed as either 3 separate medicines, combinations of single and dual / combination medicines or as triple therapy.
A list of medicines used in the analysis is detailed in Annex E.
OR
b.Patients who have had a prescription for Roflumilast most recently in November 2019 and/or December 2019.
Chemical substanceBNF code
Roflumilast0303030B0
For more details on the methodology see the Gold COPD resource