Slo-Phyllin

Hi, My con has started me on Slo-Phyllin 250mg one morning and one night. I was woundering if anyone new anything aout then and could give me some info on then as i have never had then b4 and con didn't really explain.

Thanks

XxDuckiexX

[Hidden]

Hiya,

I've never used it but I've found this info.

""Slo-phyllin prolonged release capsules contain the active ingredient theophylline. Theophylline is a type of medicine called a xanthine bronchodilator. It is used to open the airways.

Theophylline causes the muscles surrounding the airways to relax""

Not sure if that's any help.

Becca xxx

[Hidden]

This is the INFO straight from BNF on Theophylline which is WHAT Slo-phyllin is!

3.1.3 Theophylline

Theophylline is a bronchodilator used for asthma and stable chronic obstructive pulmonary disease; it is not generally effective in exacerbations of chronic obstructive pulmonary disease. It may have an additive effect when used in conjunction with small doses of beta2 agonists; the combination may increase the risk of side-effects, including hypokalaemia.

Theophylline is metabolised in the liver; there is considerable variation in plasma-theophylline concentration particularly in smokers, in patients with hepatic impairment or heart failure, or if certain drugs are taken concurrently. The plasma-theophylline concentration is increased in heart failure, cirrhosis, viral infections, in the elderly, and by drugs that inhibit its metabolism. The plasma-theophylline concentration is decreased in smokers and in chronic alcoholism and by drugs that induce liver metabolism.

Differences in the half-life of theophylline are important because its toxic dose is close to the therapeutic dose; particular care is required when introducing or withdrawing drugs that interact with theophylline. In most individuals a plasma-theophylline concentration of between 10–20 mg/litre is required for satisfactory bronchodilation, although a plasma-theophylline concentration of 10 mg/litre (or less) may be effective. Adverse effects can occur within the range 10–20 mg/litre and both the frequency and severity increase at concentrations above 20 mg/litre.

Theophylline is given by injection as aminophylline, a mixture of theophylline with ethylenediamine, which is 20 times more soluble than theophylline alone. Aminophylline injection is needed rarely for severe attacks of asthma. It must be given by very slow intravenous injection (over at least 20 minutes); it is too irritant for intramuscular use. Measurement of plasma theophylline concentration may be helpful, and is essential if aminophylline is to be given to patients who have been taking theophylline, because serious side-effects such as convulsions and arrhythmias can occasionally precede other symptoms of toxicity.

[Hidden]

Thanks that is helpful

xxx

[Hidden]

*bump* for Plumie