Approved for generic Ampyra.

[Coslet]

Starting the generic of Ampyra on Monday. GoodRx was a HUGE help in getting the cost very reasonable. For the ones on it, when did you notice any changes?

[bluejadedwho]

It made me feel terrible. Rat poison will do that to you 😉

I hope it gives you some relief however.

[Coslet in reply to bluejadedwho]

Ok..thanks for that bit of optimism.

[monkeybus in reply to bluejadedwho]

To be fair, it's bird poison.

Doesn't kill them, gives them seizures. Sends them the message that they shouldn't eat the crops.

Poison/medicine, it's all about the dose.

It's a bit much that plenty of the medicines that are routinely prescribed for us make us feel bad.

4-ap, Cymbalta, Baclofen, Gabapentin, Lyrica, Amitryptaline, Tizanidine.

Don't forget to throw in some Valium as well.

Why can't they invent some medicine with decent side effects?

4-ap rescued me. Kept me up and moving, earning money. Thanks to Coronavirus, I'm working from home now. Staggering about the house like a comedy drunk, but when I go out, 4-ap magically gets my legs moving. Every time.

[tieaknot in reply to monkeybus]

So you can just use it “as needed”? It works that fast for you? I would certainly consider that.

I’d love to be able to take something for days I have to do more walking or activity and then not take it when I’m at home just doing laundry. Hmmm....

[monkeybus in reply to tieaknot]

That's it. It's in/out, double-quick. I'm annoyed it doesn't last longer. Probably a good thing.

Of all the spasticity meds, 4-Aminopyridine reigns supreme. Just because it actually works, it doesn't simply wipe you out like those muscle relaxants.

[SongStream in reply to monkeybus]

I had to look this up and some patients while taking have experienced sensory disturbances, "such as prickling, tingling, itching, burning or cold, skin crawling or impaired sensation". Anyone?

[Coslet in reply to SongStream]

I would say the first or second day I had a few minutes where I had the sensation of being bit by a mosquito up to an ant sting. 6 days in and I haven’t had another episode of that. I have periods of the day that I have noticed a little better sense of stability. Other had spoken of decreasing or eliminating their baclofen. At the start I cut my daily consumption in half leaving the night time dose the same. So far I have not felt to need to add the pills back. Considering eliminating the daytime dose.

[julie_]

Please let us know how it is for you. I'd be interested in trying it.

Good luck

[DennyB]

I tried it for 1 month and noticed no advantage or side effects. It cost me $305 for the month. I didn't continue with it.

[fdonaire in reply to DennyB]

I had the same experience i took for about 60 days, i didn't fill effective benefits

[sisterslove]

Crossing fingers and praying this works for you.

[mariagno]

I took Ampyra for 8 months and liked it a lot. Noticed after a few days better strength And control in my legs but not enough to get out of the wheelchair.

Side effects I did not like. Insomnia, difficulty in urination, and some dizziness in the beginning.

Cost was a huge issue because I use a high deductible plan

Switched to the compounded version of 4-AP at my local pharmacy. It is not an extended version so I take 6 pills a day. The cost is $237 for 90 days.