Bisoprolol at night ?

[Prosecco1997]

hello spoke to my af nurse today , tried cutting down on my morning dose of bisop from 2.5 to 1.25 , but still made me feel ill , so now I’m going to flec in morning 50mg the eve50mg with my full dose of bisoprolol , which is3.75 mg or might just try 2.5 , my question is will this help my blood pressure in day , as when I reduce I always find it creeps up , like today , because I only took 1.25 mg so changing bisop to night nonevin day as I feel to ill

[BenHall1]

Hi,

I was put on Bisoprolol 5mg when diagnosed with paroxysmal AF in Jan 2010. Stayed on it until August 2023. When my surgery pharmacist agreed to switch me to Nebivolol 3.75mg. No sweat. Initially, when first put on Bisoprolol I was told take it in the morning ..... this gave me the side effect of random full flow nosebleeds. Complained to my GP and she said take it at night. Never had a nose bleed ever since. Ever !

The only reason I switched to Nebivolol was that the Bisoprolol finally caught up with me and made me feel like the Zombie from the Land of the Living Dead ... or worse.

No problems ever since. I can't give you a definitive answer as I do not, nor have I ever taken or been prescribed Flec. But from my research if you take Bisoprolol at night the worst of the side effects will occur when you are asleep ... all things being equal. I still take my Nebivolol at night.

Again from my research Bisoprolol is a heart rate control drug ... it is not a blood pressure control drug, although it has some properties which some healthcare professionals credit to helping a bit with BP. I also take SPECIFIC BP control drugs such as Ramipril and Felodopine.

John

[Prosecco1997 in reply to BenHall1]

Thankyou , I’ve been on bisoprolol for 13 yrs , but now getting awful side effects , so this is why I want to take at night can’t tolerate it no more

[BenHall1 in reply to Prosecco1997]

If I may suggest, contact your GP and ask for their approval to take it at night ... OR just tell them you want to try it at night. Best thing I ever did and still do.

[Prosecco1997 in reply to BenHall1]

Spoke to af nurse today , she said it was a good idea , realy hope it works for me , as day to day is a real struggle at the minute, if not I will ask my doctor for a different beta blocker to try , but been told it’s very unlikely to be the tablets , but I’m sure it is , Thankyou for your reply realy helps 🙂

[Qualipop in reply to Prosecco1997]

I was like a total zombie on bisopralol whether I took it morning or night. It was changed to a calcium channel blocker.

[BrotherThomas]

I also take 3.75 mg of bisoprolol daily. I take mine around 7.00 pm, about half an hour before dinner. My blood pressure is very stable throughout the day and within the normal range, typically 110/70.I should add that I also take ramipril early in the morning, which is a consideration.

[Ppiman]

My only thought is that bisoprolol is long acting and soon reaches what's called a "steady state" level in the blood stream. This should mean that the time of taking it becomes neither here nor there after a few days. That said, there might well in individual cases be some effect straight after a dose as I have read here of some finding a night time dose better. I've also read that blood pressure medicines taken at night reduce the BP better, but whether that applies to bisoprolol, I don't know.

Steve

[Auriculaire in reply to Ppiman]

When I was first put on Bisoprolol at 5mg a day I would take it with breakfast. Like clockwork 2 hrs later I would get a headache and start to feel awful- sluggish and groggy.

[Ppiman in reply to Auriculaire]

That’s interesting and the finger certainly points towards the drug (or I suppose it could be its effect on heart rate, output and blood pressure, perhaps. It seems to take about an hour or so to work).

Steve

[Prosecco1997]

well took my flecinide this morning, felt realy tight, heart rate higher and blood pressure aswell , but bisop usualy sorts that out , but did not take this morning due to awful side effects , good news is no awful side effects as I have previously been having , I’m sure now it’s the bisop , but keep being told it’s not ? Will take bisop dose this evening before bed and hopeful no side effects tomorrow, will my evening dose cover me for the day tomorrow