Any ideas if taking bisoprolol at night would make me less tired during the day?
I have only been taking it a week and a half (wk 1 =1.25, wk 2= 2.5), and I am not sure if it is the AF or bisoprolol that makes me need to face plant on my desk to sleep in the daytime.
Any suggestions? Thanks
Are you taking bisoprolol only when you're in afib, or are you taking it all the time, even when you're in normal rhythm?
Jim
Night works better for me.
Hi AKatieD
I must say that, when I was taking 2.5mg Bisoprolol, doing so before bed certainly helped me avoid the worst of the tiredness. Whilst AF itself can be tiring, I would suspect Bisoprolol is the reason for your desire to face-plant during the day, as the tiredness it causes can be overwhelming. Mind you, it is very early days yet and your body may well get more used to the drug as time goes on.
All the best to you, TC
Thanks everyone
I'd say its the AF. I always think its the bisoprolol, but as soon as im back in nsr, im back to normal. Hope it stops for you soon.
I have taken 2.5g Bisoporol for many years and I find spliting the dose to 1.25 morning and evening helped me very much.
Do you need to be on 2.5? These are strong drugs. I got approval from the cardiologist to cut my dose in half, took it at night and if needed to took the other half as PIP in the morning as face planting isn’t fun! Worth asking.
A week and a half is no time at all for any beta blocker in order to acclimatise to the side effects which occur in most people. After all, it brings about a number of basic changes in the body's chemicals and although bisoprolol is more cardio specific than many, it still affects the entire system. I would suggest you wait for at least a month before you can properly assess its effect on your tiredness and other functions.
Everyone is different with drugs but 1.25mg Bisop took 40 mins yo put me to sleep for for 4 or 5 hours. When zibawoke I felt dreadful!
Hi Katie - What’s your normal resting heart rate? I was on 2.5mg of Bisoprolol and literally like a zombie but with me I think was worse as HR fairly low anyway and this brought it way too low - tried 1.25 but still too low - I tried taking at night and it did help a bit but could also be due to the AFib - I can still get tired now if I’ve had an episode and off Bisoprolol (due to HR) but my AFib is not permanent
hi. How low was your heart rate when you started taking it?
Low fifties 53-55 normally
Resting HR 62 - 63 before and after starting Biso
Personally I’d keep an eye on your heart rate at different points just so you know what it is at over a period and I think most importantly how you’re feeling as everyone is different - I feel fine with a low HR but for me the Bisoprolol brought it too low and I didn’t feel fine
Thanks MWIC. I have an ECG/ HR watch so have continuous readings but not sure what I should be looking for or if resting 62 is good bad or indifferent for 59 y.o female?
As for feeling: knackered with heavy arms and legs
Not an easy answer as we’re all different and generally accepted HR should be between 60 and 100 - with me the Bisoprolol brought my HR down into 40’s but they key for me was how I felt which was bloody awful - Originally I was in 2.5mg Bisoprolol and went down to 1.25mg but whilst it may have helped a bit it wasn’t enough and I was taken off Bisoporol - few weeks later felt considerably better - I can still get tired at times but this seems very much related to effects of AFib and disturbed sleep as I often get it at night but compared to how I felt whilst in Bisoprolol I’m way better - I’m absolutely not slating Bisoprolol as I know it has some fantastic benefits - just wasn’t right for me, so if you’re not feeling good generally may be worth discussing with your GP to see if the dose of right for you or if an alternative beta blocker would be a better option for you
I saw my cardiologist last week. He said that bisopropol works for 16 hours. Better to take 1.25 am when you wake and 1.25 when you go to bed. That way you get maximum performance when you are doing your day to day activities. He said why take it at night when you are asleep. You need it more during the day. I find that works for me and don't get tired at all. I also take magnesium glycinate, coq10 vitamins C & D. I have been in persistent afib since August 2021. I am also taking edoxaban and generally feel fine.
I have not tried taking it at night tbh. I may try that and then join the discussion. My guess is it compliments other meds
Nigel
I took mine at night. Made me feel a bit better.
I was on 7.5 mg for a while and was totally zonked. I functioned much better on 2.5 mg taken at night and slept very well. It may be that 1.25 am and 1.25 pm is better, it depends on your ongoing heart rate
On my cardio's instructions I've always taken it at night. Remember it takes time for the body to adjust to any beta blocker and I remember I felt rubbish for a few weeks before it settled and i'm now fine. I take 7.5mg down from 10mg which I decided myself and I've been on it for over 35 years
I find taking mine in the evening is better. I've been in NSR for 3 1/2 years since a successful cardioversion, but was kept on 10mg bisoprolol for over 2 years, which made me pretty zombie-like. I persuaded the cardiologist to let me try lowering my dose, and got down to 5mg, which has definitely helped improve my energy.
Thanks all for the contributions. For the people who have adjusted their dose, what were you aiming for in terms of HR or what effects were you expecting from the Bisoprolol?
I am hoping will be able to drop it after cardioversion in a couple of weeks as that seemed to be the reason for taking it.
I accept it takes time to adjust and I have not been on it long, but still need to be able to work and tiredness is causing problems workwise currently.
Thanks again
I agree with RoyM, I half my 3.75 mg, not easy…..need a sharp knife. (There’s no alternative dose ). So half tablet 9am and half at 9pm. Works for me.
Hi
In NZ we have Bisoprolol in 2.5 which can be halved - line across it, 5mg, 10mg. which also has a line and narrow width on them.
cheri jOY
Hi
I take 2.5mg Bisoprolol at night.
Do you have AF?
AF can make you tired. At one stage I was taking 10mg but
it did not control my Heart Rate 156. Rapid and persistent.
Although Bisoprolol is a 24 hr lasting pill taking it at night should not make you drowsy.
I am always 47 H/R at night before AF diagnosis and H/R doesn't chamge. With me it is great for my BP. Now 123/69.
I take Diltiazem in AM for my H/r which keeps it 62-69 day resting. But after 12 months on it.
Drs tend to up you dose if the response is not satisfactory. A Heart Specialist may try you on something else like a CCB Calcium Channel Blocker. Versus BB Beta Blocker which blocks adrenaline to the heart.
Yesterday I read of another blocker.
Reactions to meds can be different for us all. Are you asmatic?
I was breathless and extremely fatigued on metoprolol and even showed 2 pauses during the night.
cheri jOY
I take mine at night, it does help
Always talk to your cardiologist before changing dosages and timings.There is a reason you are on a specific dosage.
I have found, bisiprolol will increase your weight, increase dizzyness (upon standing) and increase tiredness.
I have been allowed to alter my intake to before bedtime.
Dizzyness and tiredness have decreased.
I take both blood thinner and Bisoprolol at about 10pm before I go to bed, for that exact reason 
My experience being on just the 2.5mg Bisoprolol was significant fatigue & brain fog. I literally could hardly function at work. My Afib has been paroxsymal so I was able to convince my EP cardio to let me switch to a PIP ( pill in the pocket) approach. We thought he was weaning me off slowly over 2 weeks unfortunately I developed a rebound hypertension & high anxiety coming off it. The only reason I add this info is incase you are allowed to wean off too, to be alert for this. I did some research and found adding Magnesium ( Slow Mg two tabs Am & PM ) to my intake has helped reduce the PAC's & PVC's significantly. And my PIP protocol for the Afib is Multaq & Ranexa. I was also on those routinely for almost 2 years I think and had no Afib events so he let me switch that to PIP as well.
Of course before adjusting the dose always consult with your doctor. The fatigue you are feeling may be short term. And the benefit to trying to tolerate it now may be to your advantage in the long run. If you are in Afib daily your requirements will be different than mine. Good Luck !
I had the same issue and told to take with evening meds. Much better,even though I only take 1 25 too xx
Like many I switched it to night time. I was so tired during the day even when not in AFib. Switching my dose of 2.5 mg to night made a big difference in my energy by day.
Thanks everyone. Consultant said he did not care when I took it so going to switch to night time and see if easier to cope with
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