Switch to Edoxaban from Rivaroxaban

[riverside22]

Hi all,

I'm being switched to Edoxaban from Rivaroxaban by the gp practice, Has anyone had any problems with Edoxaban?

I've had no problems with Rivaroxaban so far.

[Vonnegut]

How different we all are! Rivaroxyban gave me the most dreadful diarrhoea so only took it for a few days- apparently that is “a common side effect” for many people but perhaps that’s us women as drugs are mostly tested on men! As I rarely have AF episodes, and those I have never last more than a couple of hours, I stopped taking them and am still here but we are all different.

[riverside22 in reply to Vonnegut]

Thanks, sorry to hear about rivaroxaban problems for you, not been an issue for me.

[Auriculaire in reply to Vonnegut]

Rivaroxaban is a recent enough drug to have been trialled with a cohort of women as well as men though the numbers were probably not equal. It is only drug trials before the 80s/ 90s that would have had very few if any female participants. The problem now is that there is still very little reporting of side effects that is sex based.

[Hidden]

Good morning riverside22,

You may like to take a look at our Edoxaban info sheet here: api.heartrhythmalliance.org... to read up a bit about the medication.

Katrina.

edoxaban info sheet

[Dippy22 in reply to Hidden]

That info sheet doesn’t mention that the dose is 30mg for people 60kg and under.

Nor that there is NO antidote.

[Hidden in reply to Dippy22]

Good morning Dippy22, our information sheets give a broad overview of the medication, any specifics such as dosages would need to be discussed with a GP or Consultant as they can vary person to person such as you mention above.

[BobD Volunteer]

Cost saving exercise I'm afraid.

[riverside22 in reply to BobD]

Yes it did say on the letter, it's cheaper so we can treat more people with afib, or words to that effect.

[Karendeena in reply to BobD]

Too right Bob, they tried this with my 90 (at the time) year old mum. I wasn't having any of it and insisted she stayed on apixaban which is what the consultant prescribed

[Cookie6]

no problems with Edoxaban at all. All the best and I hope it’s better for you.

[Hammerboy]

Hi I’ve been on Edoxaban for 5 years now with no side effects other than it takes a little longer for bleeds to stop .

[LadyLawson]

I have been on Edoxaban for three years since my Afib diagnosis without any problems or side effects that I am aware of.

[Silvasava]

Another one here on Edoxaban for 2 1/2 years with no issues

[Leggylady]

I’ve been on Edoxaban for nearly two years and haven’t been aware of any problems. Good luck!

[Gra55]

I was on Edoxoban for 2 years, was constantly short of breath and couldn't walk very far. We thought it was caused by previous heart attack and being in AF for over a year with a resting heart rate of 170!

When I had to have an operation for something else I had to stop the Edoxoban for 10 days, and was surprised to realise my shortness of breath went away. I am now on Apixoban and can walk again without getting out of breath.

Everybody is different and we react in different ways, try it if you have problems then ask to go back on previous drug.

[fairyfeathers in reply to Gra55]

I stopped Edoxaban 30mg for 5 days as I was having an operation and my backache disappeared? I have been on Edoxaban approx 7 or so months and the back aches started a month after starting it. Who knows, could just be coincidence.

[Auriculaire in reply to fairyfeathers]

Same happened with me on Apixaban . I was taken off for 8 days (Lovenox jabs substituted ) before my first hip replacement op and all my joint pain improved including that in the hip that was to be replaced!

[riverside22 in reply to Gra55]

Sorry to hear, it's amazing the different effects on different people.

[Ppiman]

I switched from rivaroxaban to apixaban and haven't noticed any difference from the change at all, with no side effects whatsoever, just twice daily dosing which doesn't have to be with food. I'm not sure if that is the case with edoxaban but I wouldn't worry about switching. It seems edoxaban as with apixaban might well be rather better anticoagulants than rivaroxaban for AF sufferers.

Steve

[Lozza53]

I was switched to Edoxaban from Rivaroxaban at the beginning of the year. The prescribing pharmacist attached to my GP surgery said that it had been advised it was a better drug?.. I took it for a couple of weeks, but it caused me to feel like my whole body was feeling my heartbeat… really weird sensation. I asked to be switched back, and have no issues with Rivaroxaban. I have since found out it is a purely financial exercise by the GP surgery.

[Dudtbin]

Ive taken edoxaban with no problems for 8 months.

[richard_jw]

After a heart attack 3 years ago, I was started on Rivaroxaban 2.5mg amongst other meds.

Early this year, I was diagnosed with Afib and started on 20mg of Rivaroxaban. After 1 month, I was experiencing terrible stomach cramps, and switched to Apixaban 5mg BD.

It did not help, and I was advised to see a Gastroenterologist, which I did privately. Apixaban is not supposed to upset the stomach, so the Gastroenterologist recommended a colonoscopy which was OK.

I am managing the stomach problems with laxatives etc.

In my case, it seems that anticoagulents taken in sufficient quantities to provide adequate anticoagulation for Afib cause this, and that's "unfortunate"

[Jimmy37]

I was switched from Edoxoban to rivaoxaban .Eboxaban gave me a sore tum. And the dose is two a day

[Cha275rL]

when I was on Rivaroxaban, I had a (very) small TIA, and was immediately put on Edoxaban. Have had no problems with it at all. Good luck.

[ozziebob]

You already understand the cost reasons behind the current general switching to Edoxaban, but I cannot speak about your individual situation. Here's an article about the reasoning ...

pharmaceutical-journal.com/...

I was offered Apixaban because it was considered the lowest risk for brain bleeds.

However the following German research seems to indicate Edoxaban is better than all other DOACs re stroke risks, and as good as Apixaban re brain bleeds. What's not to like ...

pubmed.ncbi.nlm.nih.gov/347...

So I wouldn't be as worried if offered Edoxaban now as I once would have been.

Good luck