I have been takin apixaban since early December 2020, and since the end of the year I have had almost constant indigestion (and gas). Antacid prescription meds haven't worked. I have been advised by a medical expert to change to Edoxaban as it's not loaded with lactose.
Anyone else experience the same and made a switch?
I had stomach issues with Dabigatran and changed to Edoxaban which has resolved my issues - and has the benefit of being only once a day.
Issues with Pradaxa so moved to Apixaban- no further problems but it is all very individual how we react. Hope it works for you.
Hi....I had the opposite, Edoxaban causing stomach problems (gas). I was changed to Apixaban 5mg twice daily & so far ok 👍.....all the best!!
Hello, please visit the AFA website heartrhythmalliance.org/afa... for information on anti-coagulants in our Patient Resources, all our resources are endorsed by the Dept of Health
I always take a little something with my pills, say a cookie or a few almonds etc.Have you seen this ;
I have not had indigestion feelings. But I need to eat with Apixaban. And that means a proper meal like with cheese or similar or I get a gnawing pain. It’s really important to eat with Apixaban. For some people I think ironically you could be at risk of a stomach bleed if you don’t.
Thanks to all for your advice. I have taken Apixaban with my meals and that did make a marginal improvement. So I will try the Edoxaban with it’s lower/no lactose.
You need lansoprazole from doctors nothing wrong with apixaban.ive been taking them for 7years .I have no stomach problems.i did for 3 months before I had them .felt like someone sitting on my chest.all my problems were caused by dehydration and 10 blood clots.
76 years old with A F
apixaban and hematuria 
shortness of breath
3% Afib burden and proposed medication
