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Xeralto and side effects ?

CarolineRaffan profile image
14 Replies

Hello there, Ihave been on Rivaroxaban for a few years now. Its certainly easier to take than Warfarin. However I have this year had a few episodes of vomiting, pain across the abdomen, feeling very cold etc. These have resolved, each time, but I am also a bit worried about colon health too as i seem to have got a bit of distension left side. Had 2 ultrasounds recently and have been told I dont have a hernia but do have gallstones, so have been looking into that a bit. I am going to have acupuncture for the gallstones, but am a bit worried geneally now about whether I should stop the Xarelto. My GP does do annual blood tests to check dosage, but thats all, and nobody has mentioned any adverse things about the drug. I found an American webpage (put up by a legal claim company) referring to Xarelto as "extremely dangerous" because it can cause liver damage!!! So I think it might be time to take a look at possible longer term effects, I dont khow if there are any studies available to read on this? Any help appreciated, I guess Xarelto has been on hte market a while now so there must be some kind of information available that is reliable?

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CarolineRaffan
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14 Replies
CDreamer profile image
CDreamer

You really should have regular (3-6 monthly) bloods to catch any changes in liver function but if you take as prescribed, with a main meal containing fat & protein then the risk is low, as far as I am aware. Many people don’t take as prescribed or advised so the drug is not metabolised effectively - so the liver struggles to cope with clearing the drug from your system.

I would tend to take anything on a US legal claim site with a very large pinch of salt - metaphorically speaking.

You were given anticoagulants for a very good reason & any drug will have a risk profile however benefits should always outweigh the risks - if you have AF your greatest risk is stroke - anticoagulants are a prophylactic treatment for stroke prevention so I would think very carefully and discuss with your doctor before even thinking about stopping them.

Best wishes.

CarolineRaffan profile image
CarolineRaffan in reply toCDreamer

Thankyou very much for commenting, so valuable to get others' experiences. I was thinking of cutting out fat from my diet, which could help perhaps with gallstones but apparently there are 2 kinds, one caused by cholesterol and the other by bilirubin. Thanks again, C

Tako2009 profile image
Tako2009

Hi Caroline. I changed from Xarelto to Endoxaban a while ago. I was experiencing what I would describe as IBS symptoms - and these have cleared up since the change of med. Xarelto caused me quite a few ‘gut’ problems. Liz

CarolineRaffan profile image
CarolineRaffan in reply toTako2009

Dear Tako2009, thank you for the information. Yes it is similar to IBS plus events that have led me to have the scan which revealed gallstones. I will see if my GP can change me over to Apixaban, she has not suggested any change. Take care and thanks again, Caroline

Coco51 profile image
Coco51

Hi. I take Apixaban but I do remember when I first went to the anti-coagulation clinic and they took my history I was advised to take Apixaban rather than Rivaroxaban because I had been having stomach problems (gastritis). It may be worth asking about. There seems to be a link for some people. Certainly it chimes with Tako2009's post.

Apixaban is taken 2 x daily as it has a shorter life in the body, but an advantage if you have a bleed. I too am monitored yearly and have no liver problems 🤞.

As for long term effects, I weighed up the risks and the risk of stroke seemed to outweigh any others.

CarolineRaffan profile image
CarolineRaffan in reply toCoco51

Hello Coco51, thank you so much for commenting. That sounds about right, I could talk to the GP about a change perhaps. I have never had any gastric problems previously. Much appreciated.

CDreamer profile image
CDreamer in reply toCoco51

Apixiban doesn’t require the main meal to metabolise so may be the better option - Twice a day though rather than once. I think it may be a better option for people with gastric problems.

gallstones will certainly cause the side effects that you have described.

When I had them I ended up in A+E as the pain was unbearable and presented like a heart attack

I'm not sure what you are expecting acupuncture to do for this condition. I had my gall bladder removed, no more pain

CarolineRaffan profile image
CarolineRaffan in reply to

Thank you for your reply. So far i have had some pretty infrequent episodes, so its not doing anything htat dramatic. I got it once during a visit to hte pacemaker clinic which made me wonder if stress was a factor (!). but possible I had just wolfed down a sandwich before then. I am glad the operation worked well and cleared it up for you. Caroline

Dawsonmackay profile image
Dawsonmackay

Do not blame it on the Xarelto. I have been taking it for three years and zero side effects; however, antibiotics and all sorts of pills over a number of years will affect the liver and gall bladder. You should look into liver and gall bladder flushes. I have been following this program for awhile. Since being diagnosed with Afib thirteen years ago, digestion and related things have taken a nosedive. Watch what you eat etc.

CarolineRaffan profile image
CarolineRaffan

Nice to hear from you... no it’s just that these are very new drugs and so info from others helps as pharmacists etc may not have a user-based view I suppose. Caroline

malcolmwilliams profile image
malcolmwilliams

What are gall bladder or liver flushes

CarolineRaffan profile image
CarolineRaffan in reply tomalcolmwilliams

People tell me you can use olive oil to flush out gallstones, I have not tried it.

kvmj profile image
kvmj

I've been taking Xarelto since 2017 when I switched from Eliquis. My left forearm exhibits what looks like week old bruises and the occasional purpura. I switched because insurance covered a higher percentage of Xarelto than Eliquis. That's when I found out that it was Eliquis making my hair fall out. Also, Eliquis left both forearms covered in purpura.

For me, Xarelto is better, but, everyone is different.

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