Weight gain bisoprolol

[Lisajack1]

Hi have been on 2.5 bisoprolol since end October and gained constant weight. Another 3 pounds this week. Does anyone know whether this medication causes weight gain ? Thank you

[Hidden]

I'm afraid it does for many of us. It slows the whole system down in addition to making you feel tired ....The only answer is to be extra careful with your food intake ( and more exercise..haha...if you have any energy)

It is said that your body adjusts in time so don't be too despondent.

Sandra

[Lisajack1 in reply to Hidden]

Thank you for reply.

[CDreamer]

Yes I believe so, as do many other meds.

[Mazza23]

Iam on 10mg a day and I have put on 6kg in 3years despite not eating very much

[BobD Volunteer]

Sadly these drugs slow down the whole body and since weight is stored fuel if you aren't using fuel (food) then you put on weight. Only one answer really. Easy to say but very difficult in practice. Weight gain was a side effect of the hormone implants I had for cancer treatment but somehow I managed not to put any on over the three years I had them but never lost any either when I stopped them so do wonder if some of it is in our heads? We think therefore we are to paraphrase an old one.

[Lisajack1 in reply to BobD]

Thank you

[maxred1]

Yes, sorry, as others have said, weight gain, in my case quite a lot. I cut my food drastically, upped my excercise, and no shift in my weight. Every time I went to my GP, he would comment that I was not losing any weight, etc etc..however, we got a dog, I walk it three times a day, have altered my whole life, and guess what. Slowly but surely, the weight is now coming down. I am looking and feeling better. Still on copious meds, still get my full blown AF attacks, but the weight is coming down. That's two years now......stick in. You will have to make lifestyle alterations though. IMO the only way.

[dave205]

Bisoprolol Side Effects

General

The more commonly reported side effects observed with this drug are bradycardia, dizziness, and hypotension.[Ref]

Cardiovascular

Bradycardia occurred as a dose-related event.

Cardiac failure occurred in 18.4% of patients (n=1328) compared with 22.8% of placebo-treated patients (n=1321).[Ref]

Very common (10% or more): Bradycardia (up to 15.2%)

Common (1% to 10%): Chest pain, heart failure aggravation, hypotension, cold extremities, peripheral edema, ischemia, conduction disorder, left cardiac failure, palpitation, vein disorder

Uncommon (0.1% to 1%): Atrioventricular (AV) disturbances, orthostatic hypotension

Frequency not reported: Other rhythm disturbances, claudication[Ref]

Nervous system

Very common (10% or more): Dizziness (up to 13.3%)

Common (1% to 10%): Headache, extremity numbness, cerebrovascular disorder, syncope, hypoesthesia

Frequency not reported: Vertigo, paresthesia, hypoesthesia, hyperesthesia, somnolence, decreased concentration/memory, tremor, taste abnormalities

Postmarketing reports: Unsteadiness[Ref]

Respiratory

Very common (10% or more): Dyspnea (up to 13.8%)

Common (1% to 10%): Pneumonia, bronchitis, coughing, exertional dyspnea, upper respiratory tract infection, respiratory distress, stridor, respiratory tract edema, respiratory tract hemorrhage, sinusitis

Uncommon (0.1% to 1%): Bronchospasm

Rare (0.01% to 0.1%): Allergic rhinitis[Ref]

Sinusitis occurred as a dose-related event.[Ref]

Immunologic

Very common: Antinuclear antibody (ANA) conversions (up to 15%)

Common (1% to 10%): Viral infection[Ref]

Dermatologic

Common (1% to 10%): Pruritus

Uncommon (0.1% to 1%): Sweating

Rare (0.01% to 0.1%): Itching, flushing, rash

Very rare (less than 0.01%): Alopecia, psoriasis-like rash, psoriasis exacerbation

Frequency not reported: Acne, eczema, skin irritation, cutaneous vasculitis

Postmarketing reports: Dermatitis, exfoliative dermatitis[Ref]

Gastrointestinal

Diarrhea occurred as a dose-related event.[Ref]

Common (1% to 10%): Nausea, vomiting, diarrhea, constipation, dyspepsia, epigastric pain (not food related), abdominal pain, gastritis, dry mouth

Frequency not reported: Gastric pain, peptic ulcer[Ref]

Metabolic

Common (1% to 10%): Purine metabolism disorder, carbohydrate metabolism disturbed, weight changes, cholesterol changes, potassium levels altered, blood lipid changes

Rare (0.01% to 0.1%): Increased triglycerides

Frequency not reported: Gout

Postmarketing reports: Increased uric acid and glucose[Ref]

Uric acid, serum potassium, glucose, and phosphorus increases associated with use of this drug were not of clinical importance and rarely resulted in discontinuation.[Ref]

Musculoskeletal

Common (1% to 10%): Limb pain, myalgia, arthropathy, arthralgia

Uncommon (0.1% to 1%): Muscular weakness, cramps

Frequency not reported: Back pain, neck pain, twitching[Ref]

Other

Common (1% to 10%): Asthenia, fatigue, body pain, fever, malaise

Rare (0.01% to 0.1%): Hearing disorders

Frequency not reported: Earache, tinnitus[Ref]

Fatigue and asthenia occurred as dose-related events.[Ref]

Psychiatric

Common (1% to 10%): Insomnia, anxiety

Uncommon (0.1% to 1%): Sleep disorders, depression

Rare (0.01% to 0.1%): Nightmares, hallucinations

Frequency not reported: Restlessness[Ref]

Genitourinary

Common (1% to 10%): Urinary tract infection

Rare (0.01% to 0.1%): Potency disorders

Frequency not reported: Decreased libido, Peyronie's disease, polyuria[Ref]

Hepatic

Common (1% to 10%): Hepatomegaly

Rare (0.01% to 0.1%): Increased liver enzymes (ALT, AST), hepatitis[Ref]

Transaminase elevations of 1 to 2 times the upper limit of normal were reported in 6.2% of patients, with a multiple occurrence rate of 1.9%. Generally, this increase was the result of underlying disorders or resolved with continued use of this drug.[Ref]

Hypersensitivity

Rare (0.01% to 0.1%): Hypersensitivity

Postmarketing reports: Angioedema[Ref]

Of the 15% of patients who developed positive ANA status, one-third of patients converted back to a negative titer with continued use.[Ref]

Ocular

Rare (0.01% to 0.1%): Reduced tear flow

Very rare (less than 0.01%): Conjunctivitis

Frequency not reported: Visual disturbances, ocular pain, ocular pressure[Ref]

Renal

Creatinine and BUN were associated with slightly increased levels, but these effects were generally not of clinical importance and rarely resulted in discontinuation.[Ref]

Frequency not reported: Cystitis, renal colic

Postmarketing reports: Increased creatinine and BUN[Ref]

Hematologic

During treatment with this drug, decreased levels of WBCs and platelets were not of clinical importance and rarely resulted in discontinuation.[Ref]

drugs.com/sfx/bisoprolol-si...

[GordonS]

How are you doing now Lisa, I started bisoprolol 3 weeks ago which has lowered my HR to 45-50 and despite cycling over 50 miles/week have noticed some weight gain. I assume that my lowered HR is the problem.

[Fruitcake100]

That sounds just the same as me, have put on two stone in 3 years.

I see this is an older post , wondered if you tried any other pills?

[Lisajack1]

Hi. No they say to stay on this but convinced reason for weight gain. Thank you