Loss of ploidy status information

[tarhoosier]

I posted a few weeks ago that early in my now 19 year path of prostate cancer that ploidy status was a common pathologic factor reported after surgery and occasionally in research and articles. I had not seen it mentioned in quite some time, years. I saw my oncologist yesterday and asked him about this and his response (paraphrased) was that ploidy is today considered a crude measure of tumor behavior. In the past twnety years medical science has discovered the connection of many genetic/cellular/chromosomal connections related to tumor status and behavior. An example he gave was the Human Genome Project which within these 20 years has sequenced the human genome for an inward voyage of discovery.

In other words science has marched onward significantly in 20 years and what was accepted and useful then is no longer so. We stand on the shoulders of those before us.

[kreg001]

I Googled “aneuploidy and cancer”: Aneuploidy is a common characteristic of cancer cells, where they have an abnormal number of chromosomes. It's a hallmark of cancer and is present in almost 90% of human cancers.

To be honest I thought 100% but my histology course was in 1972!

[j-o-h-n in reply to kreg001]

To be honest, I like it when you lie.....

Good Luck, Good Health and Good Humor.

j-o-h-n

[kreg001 in reply to j-o-h-n]

??

[j-o-h-n in reply to kreg001]

"To be honest"... is an expression which makes me cringe, that's all (like a finger nail rubbed on a chalkboard).

Good Luck, Good Health and Good Humor.

j-o-h-n

[kreg001 in reply to j-o-h-n]

LOL.