Chemotherapy- to do or not at 82 years ?

[Simpson80]

( I made this post earlier but am doing it again in the hope that more men in their 80’s could share their experiences if they took chemotherapy. )

I am 82 and was diagnosed last month with PCa metastatic to a few bones. Gleason 9. PSA 21 at diagnosis.

Have been put on orgovyx and been told soon will be put on an ARPI - either zytiga or xtandi.

Chemo was not mentioned.

Reading some posts here I wonder if chemo would be an important option for me?

I do 45 minutes of walking and some light exercises daily. I would not call myself strong but well kept enough to function independently. I take medicines for hypertension.

Would welcome views and experiences of those around my age who have done chemotherapy along with adt plus ARPI. Was it very tough on the body ? Was the chemo started after the arpi was added or before it?

What is the determining factor to decide if chemotherapy has to be added ?

Thank you

[Tall_Allen]

It depends on your ECOG Performance Status and your Physiological age, not your chronological age.

ncbi.nlm.nih.gov/pmc/articl...