Anyone participated in AMG 509 Clinical trial? - NCT04221542

[God_Loves_Me]

Hello

Please update us if you are participate in AMG 509.

Anything you know about AMG 509 ?

Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

[God_Loves_Me]

Got message via person chat :

my father participated in this amg 509 trial and stopped after 8 infusions as I don’t think it was successful for him.

[TurronLover]

My father participates in the clinical trial. He received around 10 infusions of different dosage. Accumulating side effects getting worse and requiring hospitalization at times. Apparently it works really well on him and the PSA went really low and density of tumor reduced in PET. Doctors says he is a very good example of good response to treatment. But the side effects makes it really difficult.

[God_Loves_Me]

recent content release on AMG-509

mdanderson.org/cancerwise/w...

A recent clinical trial involving an experimental drug called AMG 509/Xaluritamig, saw a reduction in blood levels of prostate-specific antigen (PSA), a tumor marker, in nearly half of participating patients. A quarter of participating patients whose tumors could be measured saw shrinkage on scans. This drug targets a protein called STEAP-1 on prostate tumor cells and an antigen called CD3 on T cells. Several clinical trials involving that drug are now underway at MD Anderson.