Some positive news from Lancashire, i... - Advanced Prostate...
Some positive news from Lancashire, innit?
I think I read about this fella before...good to know a ATM mutation was successful treated. Hoping to staying AR treatable for some years so these inhibitors are fully vetted. I wonder what other mutations were detected in addition to ATM?
It’s great that it only targets cancer cells. The drigs and treatments are getting better very quickly.
ATM: facingourrisk.org/info/here...
I don't have any mutations but have used olaparib with SBRT and during the initial injection of BAT. Sartor, my MO, and the head of ASTRO and a BAT/olaparib clinical trial all agreed that it would help.
Your case is even clearer. Talk to your MO.
My MO already talked about olaparib for the future in case I needed it. But there seem to be better options now as olaparib seems to work not so greatly on ATM mutations (but still better than on non mutated people). I wanted to introduce the subject of BAT giving him some references because when I hinted it he said it’s still not a well tested approach. But I would still like to talk to him about it once I am done with chemo.
It doesn't look great as monotherapy or combined with ADT.
I think the real value is with BAT and RT and some types of chemo. Even so, it is only an addition that helps the core therapies.
There are a dozen completed BAT clinical trials and another eight in progress. Given the constraints Denmeade has to work with, the trial implementations aren't optimum.
STEP-UP trial might bring BAT into more prominence. There are 20 completed or in-progress clinical trials plus many informal studies including my own study of 14 men. Even without any optimization of times, testosterone formulas, or serum T levels, the evidence speaks clearly.
I'm from Lancashire, innit isn't exclusive to the region LOL
I know but it’s UK at least! Appreciate the effort 😜😜
cancernetwork.com/view/onct....
yep! Posted already but under a different thread. I have a feeling of big news in crispr cas9 applications within 6 months
I think the CRISPR cas9 will be our salvation!
Lately I am not sleeping well because I am afraid the problem won’t be a cure itself but the length of a testing process and pipeline that was created decades ago. Knowledge is increasing so quickly nowadays and we are not keeping up on the practical development side.
Some good news…
Some good news for the holiday 
Some news from Copenhagen
Some hopeful test news:🙏🏻
Some good news for me. 
