UCLA RO says that since it's been only 4 mo since stop of 4 ms RT & 4ms orgo and my T is 80 - more t than baseline (286) may trigger cancer

[JWS13]

I thought that you could take TRT of 100 ml and you would be safe from reoccurrence.

Oncologist today at UCLA says he wants me to work with a specialist in TRT and he would only feel comfortable then giving his OK if ONLY if the testosterone specialist takes my testosterone back to ONLY my baseline of 286 and no higher.

More than 286 he says could trigger cancer.

Is that my personal safe level for microscopic cells??

I don't completely understand.

I have read and researched and I thought that you could take T up to the 4-500's (midway and be safe. ) as long as you avoid high levels of testosterone.

I have read that giving Testosterone after Radiation due to the "saturation theory" was Ok , and testosterone doesn't trigger reoccurrence!

I believe that what he was saying was those who have had PC must wait a year or two after radiation to comfortably know that you are in remission and then you can safely take TRT to raise past baseline HOWEVER I AM SPECULATING ON THIS and don't know...

Open to all Answers and suggestions & Explanations

68, PSMA Pet-no mets, psa .2, IMRT 20 tx UCLA, 4 mos Orgovyx, Testosterone 80

[Tall_Allen]

"I thought that you could take TRT of 100 ml and you would be safe from reoccurrence." The issue is whether it interferes with monitoring

[JWS13 in reply to Tall_Allen]

my understanding is that monitoring only reflects if psa is rising and a reoccurrence may have already occurred.

I thought that giving T after 4 months of orgo and 4 months of waiting is safe from reoccurrence? (it may hiinder monitoring but it shouldn't by itself CAUSE a reoccurrence...

That being said , is kishan saying "you're safe from reoccurrence as long as you take T up to your original baseline of 286 and after that it's past your personal saturation level and could feed some microscopic cancer cells that are in the process of dying ?" essentially to early to give you T past 286 baseline.

However , if you waited 5 years and your psa was at your nadir (remission) then there probably are no microscopic cells left alive to feed on the T, so the TRT can be taken higher than your 286 just not to high levels of T and then it should be safe,.

Is that essentially correct? If I am wrong please explain..TY

[Tall_Allen in reply to JWS13]

You are being monitored post-radiation to make sure the radiation killed off all your cancer cells. If your PSA increases too much they suspect recurrence and investigate further. If you take TRT, and your PSA increases, no one knows if the increase is due to T encouraging benign sources of PSA or if the increase is due to cancer that wasn't killed off. For this reason, it is imperative that you don't confuse the meaning of your PSA pattern until it has bottomed out and is stable.