Post Degaralix

[FortyWinks]

I’ve felt a bit grim for 24/36 hours after injection. Mild flu like body ache, lethargy, increased hot flushes. Found having it at 10.00am means the side effects kick in overnight and wake feeling reasonable the next morning. Had to delay the injection until 10.00pm as travelling this time. I’ve had the worst time of it ever. Really achy, frequent hot flushes, poor sleep and feeling fed up. I know it’s doing it’s thing, along with enzalutamide but feeling my quality of life balance is tipping to far the other way. Hoping I’ll feel differently by the end of today.

[Carlosbach]

I've only been on Degaralix for five months, but my reactions post implant have been different each time. Not sure what makes the difference, but I now plan to take it easy for a couple of days following each implant.

[john510185]

I'm 16 months in with Degarelix, with varying post-injection results. Nothing in the way of fever or flushes, but lethargy, considerable injection site pain and redness. Since I've tried a new regime, things have been much better. You might want to try asking the nurse to inject SUPER slowly, in the 'flabbiest' part of your abdome. I suspect some of mine have caught the muscle. Take ibuprofen and paracetamol before, and also a Clarityn tablet (TA's recommendation, I believe). Plan to do little or nothing the following day, if you can.

Dramatically better for me! I'm due an injection this Tuesday, and will be in the gym Thursday! Hope this helps!

[Oceankayaker]

I would echo the same effects from degarelix and the same advice for after care. No way to predict severity. I’ve been on degarelix for 19 months. After first bad reaction I pre-treat and continue with ibuprofen every 6 hours for at least 24-48 hours. I’m wiped out day after and just consider that a lost day

[Irwin]

Was on Degaralix for almost a year. The injections were painful. Had post injection episodes of fever, weakness, hotflashes etc. Switched to Lupron and for the last 9 years never had a painful injection, none of the mentioned episodes and it has worked so far as well as the degaralix for me. I know several others that have had the same results. Wishing you well,Irwin

[Ian99]

It’s not clear to me if the physical effects of injections vary according to the actual medication. I am on 3-monthly Zoladex injections for 2 years already. An experienced nurse makes a big difference. Changing the side each time also helps. No need for medication to mitigate SEs, at least in my case.

[StayingOptimistic]

I have had the same experience

[j-o-h-n]

Degarelix (WOW!!!)

What side effects can this medication cause?

Degarelix injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

pain, redness, swelling, hardness, or itching in the place where the medication was injected

hot flashes

excessive sweating or night sweats

nausea

constipation

diarrhea

weight gain or loss

weakness

dizziness

headache

tiredness

difficulty falling asleep or staying asleep

enlargement of the breasts

decreased sexual desire or ability

back or joint pain

Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:

hives

rash

difficulty breathing or swallowing

rapid, irregular, or pounding heartbeat

swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs

hoarseness

fluttering feeling in the chest

fainting

painful, frequent, or difficult urination; fever; or chills

Degarelix injection may cause your bones to become weaker and more brittle than they were at the beginning of your treatment. Talk to your doctor about the risks of taking this medication.

Degarelix injection may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (fda.gov/Safety/MedWatch) or by phone [phone]).

In case of emergency/overdose

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to degarelix injection.

Before having any laboratory test, tell your doctor and the laboratory personnel that you are receiving degarelix injection.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

And the worse of the worse effects is to come across j-o-h-n's post while still sober......

Do you think it would be a good idea to send some ready to drink degarelix to my ex-wife for her birthday?

Good Luck, Good Health and Good Humor.

j-o-h-n Sunday 10/01/2023 5:37 PM DST