Asking Lu177-617 (Pluvicto) and Lu177-PNT2002 Patents to reply to establish a Scorecard

[u302000]

If you are receiving Pluvicto treatment, or where part of a clinical trial of LU177-617, Lu177-PNT2002 or LU177-I&T perhaps replying with brief statement of these facts would be helpful to new patients entering this phase of mCRPC.

PSA's at each stage

Original Gleason w/ date

ADT If any w/ date

Original surgical of radiation Treatment w/type w/date

mCRPC diagnosis w/ date

Xtandi (or similar) treatment w/date and duration

Doxitaxel sessions w/ date

Lu177 type w/ # of Treatments w/ dates

Cheers,

Buddy

[Yank66]

Gleason 9, diagnosed in 2013 with PSA of 8. Prostatectomy, radiation 6 months later. PSA continued to rise-began in Lupron March, 2014 and continued with brief vacations until PSA began to rise again. Provenge July , 2019. One year of Xtandi, one year of Lynparza, docetaxal July-November, 2022. Stopped because of rising PSA and neuropathy. December, 2022 began Pluvicto at UVA with PSA of 194. Four sessions so far-PSA is now 31.

[Kian28 in reply to Yank66]

Yank66, I am starting "Pluvicto" tomorrow, July 31st, and have NO idea what to expect. Will board my dog for seven days because i can find NO info on pets. They told me the cost for each treatment would be$80,000 ...............does this seem right?? When can i have lunch with my buddies sitting in a booth?? Does a cleaning lady working in the house have to take precautions?? Any info would be greatly appreciated.

[Yank66 in reply to Kian28]

I am sure you will receive detailed instructions when you have your infusion. We did not board our dog-she just doesn’t get lap time with DH for three days and sleeps with me in a separate room. It has been hard for her to understand why she’s not getting her snuggle time with him. Three feet distance between him and others for three days (with the exception of children and pregnant women for seven days) is required. So your cleaning lady just needs to keep her distance from you. We were told that hubby had to do his own laundry (including sheets and towels) separately, and clean the bathroom thoroughly himself after 3 days. The nuclear medicine staff gives updated precautions with each infusion. Our best wishes for a good response to Pluvicto.

[u302000 in reply to Yank66]

Yank66,

Thanks for the reply and the great news and of the Pluvicto effectiveness.

I am scheduled to have my first treatment of LU177-PNT@2002 on 8 August in the NYC Clinical Trial with Dr Tagawa. We too have a 12 pound Maltease who is not going to understand the separation. I hope to have my 2nd-4th treatments closer to home at Myrtle Beach and just stay secluded in an Air B&B for the week following each. I bought a Geiger Counter from Amazon to monitor just how much of an issue the radioactive issue is. (What can I say, I'm a retired engineer!) Will update the group on my personal finding in about a mouth.

In you case, I assume you are on ADT still. Are you planning more treatment to bring the PSA down?

There is an interesting presentation of another targeted treatment in Phase 2 Clinical Trial at Myrtle Beach by Dr Shores and elsewhere most likely.

Check it out.

prostatehealthed.org

Cheers

Buddy

[u302000 in reply to u302000]

Or try

prostatehealthed.org/index....

if trouble with the the first link.

[Spyder54 in reply to u302000]

u302000,

Look forward to your well Engineered updates!

Best of luck🍀,

Mike

[u302000]

6/21 PSA 3.0

5/21 PSA 7.5 Biopsy Gleason (5+5) 10

9/21 PSA 13.4 Start Eligard ADT Quarterly

12/21 Start Proton Radiation Therapy UF PTI Jax, FL

2/22 PSA 0.08 Complete 41 sessions Proton Therapy

5/22 PSA 0.027

8/22 PSA 0.022

11/22 PSA 0.207

2/23 PSA 6.6

3/23 PSMA-PET scan result mCRPC

3/23 PSA 7.3 Xtandi 160mg, Nalterexonem4.5mg dailey

5/23 IV- Vitamin C 100gram+ Ozone Treatment weekly

5/23 PSA 25.4

6/23 1st Appointment Dr Danial Thomas, Integrative Oncologist

6/23 1st Appointment Dr Scott Tagawa, LU-177-PNT2002 PK Clinical Trial for evaluation

Cheers,

Buddy

[Spyder54 in reply to u302000]

Nice summary. Hoping for a nice turnaround on your numbers! 🍀

Best to you and yours, Mike