Study of JNJ-78278343, a T-Cell-Redirecting Agent Targeting Human Kallikrein 2 (KLK2)

[mysticmini]

I know this is a long shot, but wondering if anyone else is taking part in this clinical trial: Study of JNJ-78278343, a T-Cell-Redirecting Agent Targeting Human Kallikrein 2 (KLK2), for Advanced Prostate Cancer. My oncologist is recommending as next steps.

[TeleGuy]

Here’s a link to an article I remember from several years ago:

mskcc.org/news/precision-st...

My takeaway is that this is promising because when you give cells hk2 they want more, so they become addicted to what kills them. This article is about using it as a radioligand, not a T-cell engages like your trial.

[mysticmini in reply to TeleGuy]

thank you for sharing this!

[ehoneycutt29]

HelloWhere is trial being offered?

Thanks

Eddie

[mysticmini in reply to ehoneycutt29]

Memorial Sloane Kettering in NYC

[j-o-h-n]

and your M O is ???

Best Wishes on what you decide to do.......

j-o-h-n <===<<< Senior management is about to spike my spikes....

Good luck, Good Health and Good Humor.

j-o-h-n Friday 04/07/2023 6:27 PM DST

[Seasid]

Are you still curable? What was your last PSA and did you have a psma pet scan recently?

I would also include a link to that clinical trial if you want us to comment.

I would first make a priority to cure myself if it is still possible.

Why did you do the FDG pet scan? (I also did but it was not really recommended by my oncologist) was the fdg recommended to you because your PSA is low?

[MikeMartin]

Hello Misticmini did you decide against the KLK2 trial They are still recruiting . I am contemplating pre chemo and heared that some people are doing OK in it best regards